CAJ | 학술논문

目的：探讨老年人上消化道疾病患者幽门螺杆菌（HP）感染情况，为临床防治提供依据。方法对311例60岁以上老年人上消化道疾病患者进行胃镜检查，取胃黏膜组织作病理诊断和HP检测。同时与中青年患者进行对比分析。结果老年组患者HP阳性率显著高于青壮年组（P<0.01）。老年组患者慢性胃炎和胃溃疡HP阳性率分别为84.77%和83.67%，显著高于青壮年组（P<0.05）；老年组患者十二指肠溃疡和胃癌HP阳性率分别为71.01%和69.05%，与青壮年组相比差异无统计学意义（P>0.05）。结论老年人上消化道疾病患者与HP感染密切相关，且感染率高，应予以积极防治。
목적：탐토노년인상소화도질병환자유문라간균（HP）감염정황，위림상방치제공의거。방법대311례60세이상노년인상소화도질병환자진행위경검사，취위점막조직작병리진단화HP검측。동시여중청년환자진행대비분석。결과노년조환자HP양성솔현저고우청장년조（P<0.01）。노년조환자만성위염화위궤양HP양성솔분별위84.77%화83.67%，현저고우청장년조（P<0.05）；노년조환자십이지장궤양화위암HP양성솔분별위71.01%화69.05%，여청장년조상비차이무통계학의의（P>0.05）。결론노년인상소화도질병환자여HP감염밀절상관，차감염솔고，응여이적겁방치。
Objective To analyze the correlation between the Helicobacter pylori (HP) infections in elderly patients with upper gastrointestinal diseases, and provide evidence for clinical prevention and treatment. Method The upper gastrointestinal disease of 311 elderly patients was carried out gastroscopy inspection and took the biopsy organization to make the pathological diagnosis and the HP examination, and the young and middle-aged group was as the control at the same time. Results The positive rate of H.pylori in elderly group was signiifcantly higher than young and middle-aged group(P<0.01). The infection rate of HP detected from chronic gastritis(84.77%)and gastric ulcer(83.67%)in elderly group were signiifcantly higher than the young and middle-aged group(P<0.05). The infection rate of HP detected from duodenal ulcer (71.01%)and gastric carcinoma(69.05%)in elderly group, which was not statistically different from that of young and middle-aged group(P>0.05). Conclusion The result showed that the upper gastrointestinal disease is closely associated with the HP infection in elderly patients, the infection rate is highest in the elderly patients, and the active prevention should be performed in the clinical practice.