中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2013年
34期
312-312,313
,共2页
手足口病%热毒宁%单磷酸阿糖腺苷
手足口病%熱毒寧%單燐痠阿糖腺苷
수족구병%열독저%단린산아당선감
Hand-foot-and-mouth disease%Reduning%Adenine arabinoside monophosphate
目的：观察热毒宁联合单磷酸阿糖腺苷治疗小儿手足口病临床疗效。方法将145例手足口病患儿随机分为治疗组73例，对照组72例，对照组予以单磷酸阿糖腺苷10mg/（kg?d），治疗组在对照组治疗的基础上给予热毒宁0.5～1mL/（kg?d），1次/天，疗程7d，对临床有效率及体征的变化进行分析。结果治疗组疗效好于对照组，有效率（P＜0.01）及临床症状改善（P＜0.01）均有显著性差异。结论热毒宁联合单磷酸阿糖腺苷治疗手足口病可有效改善临床症状，减少并发症发生，缩短病程。
目的：觀察熱毒寧聯閤單燐痠阿糖腺苷治療小兒手足口病臨床療效。方法將145例手足口病患兒隨機分為治療組73例，對照組72例，對照組予以單燐痠阿糖腺苷10mg/（kg?d），治療組在對照組治療的基礎上給予熱毒寧0.5～1mL/（kg?d），1次/天，療程7d，對臨床有效率及體徵的變化進行分析。結果治療組療效好于對照組，有效率（P＜0.01）及臨床癥狀改善（P＜0.01）均有顯著性差異。結論熱毒寧聯閤單燐痠阿糖腺苷治療手足口病可有效改善臨床癥狀，減少併髮癥髮生，縮短病程。
목적：관찰열독저연합단린산아당선감치료소인수족구병림상료효。방법장145례수족구병환인수궤분위치료조73례，대조조72례，대조조여이단린산아당선감10mg/（kg?d），치료조재대조조치료적기출상급여열독저0.5～1mL/（kg?d），1차/천，료정7d，대림상유효솔급체정적변화진행분석。결과치료조료효호우대조조，유효솔（P＜0.01）급림상증상개선（P＜0.01）균유현저성차이。결론열독저연합단린산아당선감치료수족구병가유효개선림상증상，감소병발증발생，축단병정。
Objective To analyse the curative effect of Reduning combined with adenine arabinoside monophosphate on children with Hand-foot-and-mouth disease(HFMD).Methods 145 cases patients with HFMD were divided into two groups randomly. The treatment group(73case) were treated with adenine arabinoside monophosphate [10mg/(kg?d)] and contral group(72case) were treated with Reduning [0.5~1mL/(kg?d)],seven days for one period of treatment. Results The total effective rate was 95.9% in the treatment group and 83.3%in the contral group (P<0.01); Clinical symptom improvement rate were signiifcantily higher than those of the contral group (P<0.01). Conclusions Reduning combined with adenine arabinoside monophosphate on children with HFMD can improve clinical symptoms, reduce the incidence of complication and shorten the course of disease.
