CAJ | 학술논문

目的：分析基层医院救治有机磷中毒患者时，阿托品不同给药方式的疗效差异，为探索其最佳给药方法提供依据。方法回顾分析75例急性有机磷农药中毒患者的临床资料，25例进行人工间歇静脉推注阿托品法（A 组），25例采用微量泵持续静脉输注阿托品法（B 组，25例先间歇静脉推注阿托品，达阿托品化后再用微量泵泵入阿托品（C 组），分析比较三组阿托品化时间、用量、住院时间、疗效以及不良反应和并发症。结果 C 组阿托品化时间、用量、住院时间、阿托品过量、不足中毒、用量、尿潴留和多器官功能损害等明显降低而治愈率显著提高（P ＜0.05）。结论采用阿托品人工静脉推注,待患者阿托品化再予以微量泵给药，不仅起效速度快，而且恒速恒量，不良反应少，疗效较好，值得临床推广使用。
목적：분석기층의원구치유궤린중독환자시，아탁품불동급약방식적료효차이，위탐색기최가급약방법제공의거。방법회고분석75례급성유궤린농약중독환자적림상자료，25례진행인공간헐정맥추주아탁품법（A 조），25례채용미량빙지속정맥수주아탁품법（B 조，25례선간헐정맥추주아탁품，체아탁품화후재용미량빙빙입아탁품（C 조），분석비교삼조아탁품화시간、용량、주원시간、료효이급불량반응화병발증。결과 C 조아탁품화시간、용량、주원시간、아탁품과량、불족중독、용량、뇨저류화다기관공능손해등명현강저이치유솔현저제고（P ＜0.05）。결론채용아탁품인공정맥추주,대환자아탁품화재여이미량빙급약，불부기효속도쾌，이차항속항량，불량반응소，료효교호，치득림상추엄사용。
Objective To explore the effects of different atropine medications in remedy of severely acute organophosphorus pesticide. Methods A retrospective study were performed.This study was carried out in 75 patients with acute organophosphorus pesticide poisoning. The patients were divided into three groups according atropine medications: Group A(25 cases), were treated with intravenous injection of atropine and artificial; Group B(25 cases)directly with micro pump delivery, Group C(25 cases)achieved using micro-pump after atropine administration patients are atropine artificial intravenous injection, the patient achieved using micro-pump after atropine administration; Compared the efficacy and complications among the three groups. Results There is significant difference between minim continuous pump after atropine administration and interval injecting or minim continuous pump. As a result, the patients in Group C were more effective and fewer complications than that in Group A and C. Conclusion Using micro-pump after atropine administration artificial intravenous injection of atropine was the better effect, it has proved to be a fine medication.