CAJ | 학술논문

目的：观察分析依达拉奉用于围术期脊髓保护的临床效果。方法选取我院接受减压内固定治疗的脊髓损伤患者共60例，依照入院顺序随机平均分为观察组与对照组，对照组常规方式予以减压内固定手术治疗，观察组在对照组基础上加用依达拉奉保护脊髓。结果观察组术后30min 脑脊液自由基平均水平（57.9±5.18），与术前相比无统计学差异（P ＞0.05），且明显低于对照组同期水平（P ＜0.05）。观察组术后2周及3个月 JOA 评分均明显高于对照组（P ＜0.05）。结论依达拉奉用于围术期可有效控制脑脊液自由基水平、提升 JOA 分数，脊髓保护效果显著。
목적：관찰분석의체랍봉용우위술기척수보호적림상효과。방법선취아원접수감압내고정치료적척수손상환자공60례，의조입원순서수궤평균분위관찰조여대조조，대조조상규방식여이감압내고정수술치료，관찰조재대조조기출상가용의체랍봉보호척수。결과관찰조술후30min 뇌척액자유기평균수평（57.9±5.18），여술전상비무통계학차이（P ＞0.05），차명현저우대조조동기수평（P ＜0.05）。관찰조술후2주급3개월 JOA 평분균명현고우대조조（P ＜0.05）。결론의체랍봉용우위술기가유효공제뇌척액자유기수평、제승 JOA 분수，척수보호효과현저。
Objective To observe the effect of edaravone for protection with perioperative spinal effect. Methods 60 cases of patients with spinal cord injury, divided into the observation group and the control group, the control group treated with decompression and internal fixation operation, the observation group based on the control group used edaravone to protect spinal cord .Results The average of free radicals in cerebrospinal fluid in observation group were lower than those of the control group30min after operation(P<0.05), the JOA score of observation group were higher 2 weeks and 3 months after operation(P<0.05). Conclusion The effect of edaravone protect spinal cord significantly.