中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2013年
35期
6-8
,共3页
林克宣%刘冠贤%吴勇%黄成文%石咏军%李幼奇%钟伟强
林剋宣%劉冠賢%吳勇%黃成文%石詠軍%李幼奇%鐘偉彊
림극선%류관현%오용%황성문%석영군%리유기%종위강
肾活检%肾脏病理%临床表现
腎活檢%腎髒病理%臨床錶現
신활검%신장병리%림상표현
Renal biopsy%Renal pathology%Clinical manifestation
目的:研究临床表现与肾脏病理的关系,明确肾活检的临床价值,提高慢性肾脏病的诊治水平。方法回顾性分析308例肾活检病例的病理类型与临床类型、尿检的关系。结果原发性肾小球疾病(PGN)表现为无症状尿检异常(AUA)、肾炎综合征(NiS)、肾病综合征(NS)、急性肾衰竭(ARF)、慢性肾衰竭(CRF)的比例分别是18.8%、25.2%、42.8%、7.2%、6.0%,而继发性肾小球疾病(SGN)分别是3.4%、44.8%、25.9%、6.9%、19.0%,PGN 与 SGN 在表现为 AUA、NiS、NS、CRF 的差异有统计学意义(P <0.05),在表现为ARF 差异无统计学意义(P >0.05)。PGN 表现为单纯血尿、少量蛋白尿、中量蛋白尿、大量蛋白尿的比例分别为5.6%、27.2%、29.2%、38.0%,而 SGN 分别是3.4%、20.7%、41.4%、34.5%,PGN 与 SGN 在血尿、蛋白尿差异无统计学意义(P >0.05)。结论临床方面 PGN以 NS 最常见,SGN 以 NiS 最常见,尿检方面 PGN 中以大量蛋白尿最常见,SGN 中以中量蛋白尿最常见。
目的:研究臨床錶現與腎髒病理的關繫,明確腎活檢的臨床價值,提高慢性腎髒病的診治水平。方法迴顧性分析308例腎活檢病例的病理類型與臨床類型、尿檢的關繫。結果原髮性腎小毬疾病(PGN)錶現為無癥狀尿檢異常(AUA)、腎炎綜閤徵(NiS)、腎病綜閤徵(NS)、急性腎衰竭(ARF)、慢性腎衰竭(CRF)的比例分彆是18.8%、25.2%、42.8%、7.2%、6.0%,而繼髮性腎小毬疾病(SGN)分彆是3.4%、44.8%、25.9%、6.9%、19.0%,PGN 與 SGN 在錶現為 AUA、NiS、NS、CRF 的差異有統計學意義(P <0.05),在錶現為ARF 差異無統計學意義(P >0.05)。PGN 錶現為單純血尿、少量蛋白尿、中量蛋白尿、大量蛋白尿的比例分彆為5.6%、27.2%、29.2%、38.0%,而 SGN 分彆是3.4%、20.7%、41.4%、34.5%,PGN 與 SGN 在血尿、蛋白尿差異無統計學意義(P >0.05)。結論臨床方麵 PGN以 NS 最常見,SGN 以 NiS 最常見,尿檢方麵 PGN 中以大量蛋白尿最常見,SGN 中以中量蛋白尿最常見。
목적:연구림상표현여신장병리적관계,명학신활검적림상개치,제고만성신장병적진치수평。방법회고성분석308례신활검병례적병리류형여림상류형、뇨검적관계。결과원발성신소구질병(PGN)표현위무증상뇨검이상(AUA)、신염종합정(NiS)、신병종합정(NS)、급성신쇠갈(ARF)、만성신쇠갈(CRF)적비례분별시18.8%、25.2%、42.8%、7.2%、6.0%,이계발성신소구질병(SGN)분별시3.4%、44.8%、25.9%、6.9%、19.0%,PGN 여 SGN 재표현위 AUA、NiS、NS、CRF 적차이유통계학의의(P <0.05),재표현위ARF 차이무통계학의의(P >0.05)。PGN 표현위단순혈뇨、소량단백뇨、중량단백뇨、대량단백뇨적비례분별위5.6%、27.2%、29.2%、38.0%,이 SGN 분별시3.4%、20.7%、41.4%、34.5%,PGN 여 SGN 재혈뇨、단백뇨차이무통계학의의(P >0.05)。결론림상방면 PGN이 NS 최상견,SGN 이 NiS 최상견,뇨검방면 PGN 중이대량단백뇨최상견,SGN 중이중량단백뇨최상견。
Objective To investigate the relationship between clinical manifestation and pathology, and clarify the clinical value of renal biopsy, in order to improve the diagnosis and treatment of chronic kidney disease. Methods 308 cases with renal biopsy were analyzed retrospectively, in cluding the relationship between pathological type and clinical type, hematuria, proteinuria. Results Primary glomerulonephritis(PGN)performanced with asymptomatic urinary abnormalities(AUA), nephritic syndrome(NiS), nephrotic syndrome(NS), acute renal failure(ARF) and chronic renal failure (CRF)were 18.8%, 25.2%, 42.8%, 7.2% and 6.0%. The performance in secondary glomerulonephritis(SGN)was 3.4%, 44.8%, 25.9%, 6.9% and 19.0%. The different performance between PGN and SGN in AUA, NIS, NS and CRF was statistically significant(P<0.05), yet in ARF was insignificant(P>0.05). PGN performanced with simple hematuria, a small amount of proteinuria, moderate proteinuria and heave proteinuria were 5.6%, 27.2%, 29.2% and 38.0%. The performance in SGN was 3.4%, 20.7%, 41.4% and 34.5%. There was no significant difference(P>0.05) between PGN and SGN in hematuria and proteinuria. Conclusions NS is the most common type in PGN, and NIS is most popular for SGN. The heave proteinuria is the most common type in PGN, and moderate proteinuria is the most common type in SGN.