激光杂志
激光雜誌
격광잡지
LASER JOURNAL
2014年
1期
56-57
,共2页
杨梅%胡雪原%孙立力%王红%万坤%张景勍
楊梅%鬍雪原%孫立力%王紅%萬坤%張景勍
양매%호설원%손립력%왕홍%만곤%장경경
去甲氧基姜黄素%纳米脂质载体%HPLC法%含量测定
去甲氧基薑黃素%納米脂質載體%HPLC法%含量測定
거갑양기강황소%납미지질재체%HPLC법%함량측정
Deme-thoxycurcumin%lipid nanoparticles%concent
目的：建立HPLC法测去甲氧基姜黄素纳米粒脂质载体(NLC)中药物含量的方法。方法：采用HPLC法测定纳米脂质载体(NLC)中药物的含量。结果表明去甲氧基姜黄素在420nm处有最大吸收，浓度在2.04至52.5mg·mL-1时与吸光度呈良好的线性关系,回归方程为：Y =121.29C X -296.19，r =0.9997( n =6)；平均回收率为99.19%，RSD为0.79%。结论：本方法操作简单，且稳定性、准确度和精密度均符合要求，可用于NLC制剂中去甲氧基姜黄素含量的测定。
目的：建立HPLC法測去甲氧基薑黃素納米粒脂質載體(NLC)中藥物含量的方法。方法：採用HPLC法測定納米脂質載體(NLC)中藥物的含量。結果錶明去甲氧基薑黃素在420nm處有最大吸收，濃度在2.04至52.5mg·mL-1時與吸光度呈良好的線性關繫,迴歸方程為：Y =121.29C X -296.19，r =0.9997( n =6)；平均迴收率為99.19%，RSD為0.79%。結論：本方法操作簡單，且穩定性、準確度和精密度均符閤要求，可用于NLC製劑中去甲氧基薑黃素含量的測定。
목적：건립HPLC법측거갑양기강황소납미립지질재체(NLC)중약물함량적방법。방법：채용HPLC법측정납미지질재체(NLC)중약물적함량。결과표명거갑양기강황소재420nm처유최대흡수，농도재2.04지52.5mg·mL-1시여흡광도정량호적선성관계,회귀방정위：Y =121.29C X -296.19，r =0.9997( n =6)；평균회수솔위99.19%，RSD위0.79%。결론：본방법조작간단，차은정성、준학도화정밀도균부합요구，가용우NLC제제중거갑양기강황소함량적측정。
Objective: To establish the method determination of deme-thoxycurcumin from NLC. Method: HPLC assay was used, l=420 nm. Result: It had good linearity with the 2.04-52.5mg·mL-1 concentration range of deme-thoxycurcumin . There-gression is Y =121.29C X -296.19, r =0.9997( n =6) The recovery from the sample was 99.19%, RSD was 0.79%.Conclusion:This method is could used to quality standards for deme-thoxycurcumin of NLC.
