CAJ | 학술논문

目的：观察婴儿高压氧舱(HBO)治疗新生儿缺氧缺血性脑病(HIE)促进患儿智能康复的近期、远期疗效.方法：治疗组54例HIE患儿在传统基础治疗上采用婴儿高压氧舱治疗,10 d为1个疗程,而对照组25例HIE患儿单纯采用传统治疗,两组患儿均按双盲原则,于生后10 d、19 d行新生儿行为神经(NBNA)测定,两组进行对比,并观察远期后遗症发生率.结果：HBO组19d时NBNA评分明显高于对照组(P<0.01),两者比较有非常显著性差异,远期后遗症发生率明显少于对照组(P<0.05).结论：HBO不仅可显著提高患儿的近期疗效,而且能够明显改善患儿的远期预后,减少后遗症的发生,防治智力低下,可作为新生儿HIE的一种辅助治疗方法.
목적：관찰영인고압양창(HBO)치료신생인결양결혈성뇌병(HIE)촉진환인지능강복적근기、원기료효.방법：치료조54례HIE환인재전통기출치료상채용영인고압양창치료,10 d위1개료정,이대조조25례HIE환인단순채용전통치료,량조환인균안쌍맹원칙,우생후10 d、19 d행신생인행위신경(NBNA)측정,량조진행대비,병관찰원기후유증발생솔.결과：HBO조19d시NBNA평분명현고우대조조(P<0.01),량자비교유비상현저성차이,원기후유증발생솔명현소우대조조(P<0.05).결론：HBO불부가현저제고환인적근기료효,이차능구명현개선환인적원기예후,감소후유증적발생,방치지력저하,가작위신생인HIE적일충보조치료방법.
Objective:To observe the long-time effects of the hyperbaric oxygen (HBO) therapy on the promotion of intellectual in infants with severe hypoxic ischemic encephalopathy (HIE).Methods:The treatment group (fifty-four cases of (HIE) were given comprehensive therapy combine with Hyperbaric oxygen therapy, and the treatment course was fifteen days. The control group (twenty-five cases) was given comprehensive treatment. Neonatal Behavioral Neurological Assessment (NBNA) assay was employed at 10 and 19 d after born in two groups according the double-blind way. Two groups were compared and the long-term the incidence of sequel was observed. Results:The score of NBNA in the HBO group was significantly higher at 19d (p<0.01) and the incidence of log-term sequel was lower (P<0.05) d compared with that in the control group,. The score of NBNA in the HBO group was significantly higher at 19d (p<0.01) and the incidence of log-term sequel was lower (P<0.05) compared with that in the control group. Conclusions:HBO therapy, which could be regarded as assistant therapeutic methods of HIE, could promote the short-time intellectual rehabilitation, as well as the long-time one in infants with severe HIE, and it also might be benefit t the prevention of mental retardation