CAJ | 학술논문

血管内皮生长因子（VEGF）在类风湿关节炎的血管新生中起着重要的作用，VEGF主要是通过与血管内皮细胞表面特异受体结合发挥生物学效应。对VEGF及其受体的功能，缺氧、细胞因子及炎症因子对VEGF及其受体的表达调控以及VEGF及其受体与RA病理变化、病情改变和治疗作用的相关性进行探讨。
혈관내피생장인자（VEGF）재류풍습관절염적혈관신생중기착중요적작용，VEGF주요시통과여혈관내피세포표면특이수체결합발휘생물학효응。대VEGF급기수체적공능，결양、세포인자급염증인자대VEGF급기수체적표체조공이급VEGF급기수체여RA병리변화、병정개변화치료작용적상관성진행탐토。
Vascular endothelial growth factor (VEGF) plays an important role in angiogenesis in the patients with rheumatoid arthritis (RA). VEGF gives play to its biological effects through combining with the specific receptor of vascular endothelial cell surface. The authors investigated the functions of VEGF and its receptor, regulations of anoxia, cytokines and inflammatory factors on the expressions of VEGF and its receptor, and the correlation between VEGF or its receptor and RA pathological changes, and between disease condition and treatment.