医学信息
醫學信息
의학신식
MEDICAL INFORMATION
2014年
2期
52-52
,共1页
类风湿关节炎%类风湿因子%抗环瓜氨酸肽抗体%疾病活动指数28%骨侵蚀%肺间质纤维化
類風濕關節炎%類風濕因子%抗環瓜氨痠肽抗體%疾病活動指數28%骨侵蝕%肺間質纖維化
류풍습관절염%류풍습인자%항배과안산태항체%질병활동지수28%골침식%폐간질섬유화
Rheumatoid arthritis%Rheumatoid factor%Anti-cyclic citrul inated peptide antibodies%Disease Activity Index 28%Bone erosion%Interstitial pulmonary fibrosis
目的:探讨类风湿因子(RF)、抗环瓜氨酸(CCP)抗体与类风湿关节炎(RA)疾病活动性评分及关节损害、肺间质纤维化的关系。方法分析抗 CCP抗体、RF与类风湿关节炎活动性评分(DAS28)、关节骨侵蚀、肺间质纤维化的关系。结果合并肺间质纤维化的 RA患者中,RF高滴定度阳性(19.2%)所占百分比高于阴性者(11.5%),抗CCP抗体高滴定度阳性(66.7%)所占百分比高于阴性者(14.8%),差异有统计学意义(P<0.05)。结论高滴定度RF和抗CCP抗体可能与RA患者合并肺间质纤维化相关。
目的:探討類風濕因子(RF)、抗環瓜氨痠(CCP)抗體與類風濕關節炎(RA)疾病活動性評分及關節損害、肺間質纖維化的關繫。方法分析抗 CCP抗體、RF與類風濕關節炎活動性評分(DAS28)、關節骨侵蝕、肺間質纖維化的關繫。結果閤併肺間質纖維化的 RA患者中,RF高滴定度暘性(19.2%)所佔百分比高于陰性者(11.5%),抗CCP抗體高滴定度暘性(66.7%)所佔百分比高于陰性者(14.8%),差異有統計學意義(P<0.05)。結論高滴定度RF和抗CCP抗體可能與RA患者閤併肺間質纖維化相關。
목적:탐토류풍습인자(RF)、항배과안산(CCP)항체여류풍습관절염(RA)질병활동성평분급관절손해、폐간질섬유화적관계。방법분석항 CCP항체、RF여류풍습관절염활동성평분(DAS28)、관절골침식、폐간질섬유화적관계。결과합병폐간질섬유화적 RA환자중,RF고적정도양성(19.2%)소점백분비고우음성자(11.5%),항CCP항체고적정도양성(66.7%)소점백분비고우음성자(14.8%),차이유통계학의의(P<0.05)。결론고적정도RF화항CCP항체가능여RA환자합병폐간질섬유화상관。
Objective:To investigate the rheumatoid factor (RF),anti cyclic citrul inated peptide (CCP) antibody and rheumatoid arthritis (RA) interstitial fibrosis and the relationship between disease activity score and knee injury,lung. Methods:analysis of anti CCP antibodies,RF and rheumatoid arthritis activity score (DAS28),fibrosis,lung relationship between joint bone erosion. Results:pulmonary interstitial fibrosis in patients with RA,RF high titer positive (19.2%) percentage higher than the negative ones (11.5%),anti CCP antibody with high titer was positive (66.7%)percentage higher than the negative ones (14.8%),the dif erence was statistical y significant (P<0.05). Conclusion:high titer of RF and anti CCP antibody may be associated with RA patients with pulmonary interstitial fibrosis related.