CAJ | 학술논문

目的：采用随机对照研究观察柴胡加龙骨牡蛎汤化裁方对酒精依赖症患者生存质量的影响。方法将56名酒精依赖症患者随机分为2组，分别服用配方颗粒制剂的柴胡加龙骨牡蛎汤化裁方（治疗组）或安慰剂（对照组）4周。并以健康状况问卷（Short Form 36 Health Survey Questionnaire，SF-36）为研究工具，量化评估柴胡加龙骨牡蛎汤化裁方对酒精依赖症患者生活质量的影响。结果经治疗前后SF-36计分数据比较，治疗组在服药4周后，在生理机能、生理职能、躯体疼痛、一般健康状况、精力、精神健康6个维度上的得分均高于对照组。结论柴胡加龙骨牡蛎汤化裁方可以改善酒精依赖症患者的生活质量。
목적：채용수궤대조연구관찰시호가용골모려탕화재방대주정의뢰증환자생존질량적영향。방법장56명주정의뢰증환자수궤분위2조，분별복용배방과립제제적시호가용골모려탕화재방（치료조）혹안위제（대조조）4주。병이건강상황문권（Short Form 36 Health Survey Questionnaire，SF-36）위연구공구，양화평고시호가용골모려탕화재방대주정의뢰증환자생활질량적영향。결과경치료전후SF-36계분수거비교，치료조재복약4주후，재생리궤능、생리직능、구체동통、일반건강상황、정력、정신건강6개유도상적득분균고우대조조。결론시호가용골모려탕화재방가이개선주정의뢰증환자적생활질량。
Objective To investigate the influence of modified Chaihu Plus Longgu Muli Tang on quality of life in the patients with alcohol dependence by using a randomized controlled study. Methods The patients with alcohol dependence (n=56) were randomly divided into two groups, and treatment group was treated with granules formulation of Chaihu plus Longgu Muli Tang and control group was treated with placebo for 4 weeks. With a research tool of health status questionnaire (Short Form 36 Health Survey Questionnaire:SF-36), the influence of Chaihu plus Longgu Muli Tang on quality of life in patients with alcohol dependence was reviewed quantatively. Results After 4 weeks, through the comparison in SF-36 scoring data before and after treatment, scores of 6 dimensions of physical functioning (PF), role of physiology (RP), bodily pain (BP), general health (GH), vitality (VT) and mental health (MH) were all significantly higher in treatment group than those in control group, while comparison in dimensions of social functioning (SF) and role emotional (RE) showed there was no statistically significant difference. Conclusion Modified Chaihu Plus Longgu Muli Tang can improve the quality of life in patients with alcohol dependence.