CAJ | 학술논문

目的：探讨益气活血方对髋部骨折术后下肢深静脉血栓形成（DVT）的预防作用。方法收集2008年1月～2012年12月，接受手术治疗的髋部骨折患者106例，随机分为观察组与对照组，各53例，对照组常规应用低分子肝素钙治疗，观察组在对照组的基础上予以益气活血方口服，比较两组的凝血功能指标、DVT及不良反应发生率。结果两组治疗后FIB以及D-Dimer均显著降低，PT及APTT均显著延长，观察组与对照组比较差异有统计学意义（P＜0.05）；观察组的DVT发生率为3.77%，显著低于对照组的16.98%；观察组的不良反应发生率为0，与对照组的3.77%差异无统计学意义（P＞0.05）。结论益气活血方可显著改善髋部骨折手术患者的凝血功能，预防术后DVT发生，不良反应少，值得推广应用。
목적：탐토익기활혈방대관부골절술후하지심정맥혈전형성（DVT）적예방작용。방법수집2008년1월～2012년12월，접수수술치료적관부골절환자106례，수궤분위관찰조여대조조，각53례，대조조상규응용저분자간소개치료，관찰조재대조조적기출상여이익기활혈방구복，비교량조적응혈공능지표、DVT급불량반응발생솔。결과량조치료후FIB이급D-Dimer균현저강저，PT급APTT균현저연장，관찰조여대조조비교차이유통계학의의（P＜0.05）；관찰조적DVT발생솔위3.77%，현저저우대조조적16.98%；관찰조적불량반응발생솔위0，여대조조적3.77%차이무통계학의의（P＞0.05）。결론익기활혈방가현저개선관부골절수술환자적응혈공능，예방술후DVT발생，불량반응소，치득추엄응용。
Objective To investigate the effect of Yiqi Huoxue Fang on deep venous thrombosis(DVT)of lower extremity after surgery for hip fracture. Methods 106 cases of hip fracture patients underwent surgery from January 2008 to December 2012 were randomly divided into observation group and control group, 53 cases in each group.The control group received low molecular weight heparin treatment, the observation group received orally Yiqi Huoxue Fang on the basis of control group, the coagulation parameters, the incidence of DVT and adverse reactions in the two groups were compared. Results After treatment, the FIB and D-Dimer in the two groups were significantly lower, PT and APTT were significantly prolonged. Observation group and control group was significant difference(P < 0.05);the incidence of DVT in observation group was 3.77%,significantly lower than16.98%in the control group;the adverse reaction incidence of observation group was0.0%, which had no significant difference with 3.77%in the control group(P >0.05). Conclusion Yiqi Huoxue Fang can significantly improve the coagulation function of patients undergoing hip fracture, prevent the occurrence of postoperative DVT, and has less adverse reactions. It should be widely applied.