CAJ | 학술논문

目的：考察复方月见草油软胶囊的减肥作用。方法清洁级雄性SD大鼠50只，体质量120～180 g。根据人体推荐量，设复方月见草油软胶囊低、中、高剂量（0．15、0．30、0．90 g／kg ）组、模型对照组和空白对照组，连续给药30 d ，期间记录每只动物的加食量、剩食量，定期称量体质量，实验结束时测定脂肪重量，计算脂／体比值。结果高剂量组动物第3 w、实验末体质量、体质量总增重低于模型对照组，差异有统计学意义（P ＜0．05），实验后体内脂肪重量明显低于模型对照组，差异有统计学意义（P ＜0．01）。各剂量组动物进食量、食物利用率、脂体比值与模型对照组比较无明显差异（P ＞0．05）。结论复方月见草油软胶囊对动物具有减肥功能。
목적：고찰복방월견초유연효낭적감비작용。방법청길급웅성SD대서50지，체질량120～180 g。근거인체추천량，설복방월견초유연효낭저、중、고제량（0．15、0．30、0．90 g／kg ）조、모형대조조화공백대조조，련속급약30 d ，기간기록매지동물적가식량、잉식량，정기칭량체질량，실험결속시측정지방중량，계산지／체비치。결과고제량조동물제3 w、실험말체질량、체질량총증중저우모형대조조，차이유통계학의의（P ＜0．05），실험후체내지방중량명현저우모형대조조，차이유통계학의의（P ＜0．01）。각제량조동물진식량、식물이용솔、지체비치여모형대조조비교무명현차이（P ＞0．05）。결론복방월견초유연효낭대동물구유감비공능。
Objective To investigate the effects of Compound Scabish Oil Soft Capsule on weight reduction . Methods Fifty rats were randomly divided into 5 groups :low-dose ,middle-dose and high-dose of Scabish Oil Soft Capsule (0 .15 ,0 .30 ,0 .90 g/kg) model group and blank control group ,they were given succes-sive administration in 30 d ,the amount of food-gain ,food residual and body weight ,fat mass were deter-mined during the experiment .Results The body weight in the third week and end of the experiment ,total weight-gain after experiment of the high-dose group were lower than the control group (P<0 .05) and the body fat weight were significantly lower than the control group (P<0 .01) .Compared with control group , the food intake ,food utilization rate and the ratio of fat mass to body weight of the rats in each dose group had no significant difference (P >0 .05) .Conclusion Scabish Oil Soft Capsule has the function of weight reduction .