CAJ | 학술논문

目的：探讨Behcet病（Behcet's disease，BD）患者血清TNF-α、IFN-γ、MCP-1的水平。 　　方法：BD患者25例，对照组为健康志愿献血员30例，抽取血清检测TNF-α、IFN-γ、MCP-1等指标。 　　结果：BD活动期患者TNF-α、IFN-γ、MCP-1均高于健康对照组，差异有统计学意义。 　　结论：BD活动期患者TNF-α、IFN-γ、MCP-1异常升高，可能与BD的发病机制有关。
목적：탐토Behcet병（Behcet's disease，BD）환자혈청TNF-α、IFN-γ、MCP-1적수평。 　　방법：BD환자25례，대조조위건강지원헌혈원30례，추취혈청검측TNF-α、IFN-γ、MCP-1등지표。 　　결과：BD활동기환자TNF-α、IFN-γ、MCP-1균고우건강대조조，차이유통계학의의。 　　결론：BD활동기환자TNF-α、IFN-γ、MCP-1이상승고，가능여BD적발병궤제유관。
AIM:To study the serum levels of TNF-α, IFN-γand MCP-1 in patients with Behcet's disease ( BD) . METHOS:Twenty-five patients with BD as study group and 30 normal volunteers as control group were inclued in the study.Serum levels of TNF-α, IFN-γand MCP-1 were measured. RESULTS:Serum levels of TNF-α, IFN-γand MCP-1 were significant higher in active BD patients than in normal controls. CONCLUSION:Our results suggest that serum levels of TNF-α, IFN-γand MCP-1 abnormally increased in active BD paiteins.The higher expression may play a role in the pathogenesis of BD.