CAJ | 학술논문

目的：调查沈阳市风雨坛社区2型糖尿病（ type 2 diabetes mellitus， T2DM ）人群中糖尿病视网膜病变（ diabetic retinopathy ， DR）患病率及相关危险因素。 　　方法：2011年筛查社区T2DM患者457例，2013年复查其中的92例，并新增312例T2 DM患者，调查其基本情况及生活方式，并进行糖尿病视网膜病变筛查，运用Logistic多元回归分析相关危险因素。 　　结果：风雨坛社区2011年和2013年DR患病率分别为15．8％和41．2％。 DR与NDR组比较，年龄、DM 家族史、DM 病程、空腹和餐后2 h 血糖、糖化血红蛋白（HbA1c）、总胆固醇（TC）、血清肌酐（Scr）、收缩压（SBP）及高、低密度脂蛋白胆固醇（ HDL-C、LDL-C ）差异有统计学意义（ P＜0．05）。 Logistic 回归分析表明：年龄、DM病程、HbA1 c、SBP 及 HDL-C 是DR 的独立危险因素。2013年参与复查的92例DM患者，DR进展和新发共31例（33．7％），主要与血糖控制不良有关。 　　结论：风雨坛社区居民DR患病率远高于我国北方的其他研究，主要与患者DM病程长、血糖控制不良、对DM及其眼病的重视程度不够以及高血压、高血脂等全身疾病的共同作用相关。
목적：조사침양시풍우단사구2형당뇨병（ type 2 diabetes mellitus， T2DM ）인군중당뇨병시망막병변（ diabetic retinopathy ， DR）환병솔급상관위험인소。 　　방법：2011년사사사구T2DM환자457례，2013년복사기중적92례，병신증312례T2 DM환자，조사기기본정황급생활방식，병진행당뇨병시망막병변사사，운용Logistic다원회귀분석상관위험인소。 　　결과：풍우단사구2011년화2013년DR환병솔분별위15．8％화41．2％。 DR여NDR조비교，년령、DM 가족사、DM 병정、공복화찬후2 h 혈당、당화혈홍단백（HbA1c）、총담고순（TC）、혈청기항（Scr）、수축압（SBP）급고、저밀도지단백담고순（ HDL-C、LDL-C ）차이유통계학의의（ P＜0．05）。 Logistic 회귀분석표명：년령、DM병정、HbA1 c、SBP 급 HDL-C 시DR 적독립위험인소。2013년삼여복사적92례DM환자，DR진전화신발공31례（33．7％），주요여혈당공제불량유관。 　　결론：풍우단사구거민DR환병솔원고우아국북방적기타연구，주요여환자DM병정장、혈당공제불량、대DM급기안병적중시정도불구이급고혈압、고혈지등전신질병적공동작용상관。
AIM:To investigate the prevalence rate and risk factors of diabetic retinopathy ( DR) in type 2 diabetes mellitus (T2DM) in Fengyutan community in Shenyang. METHODS: Totally 457 community residents with T2DM were selected in 2011.Ninety-two of these people accepted the reexamination in 2013.Besides, there were 312 residents with T2DM joined in the study in the same year.Basic condition and life style were investigated, and diabetic retinopathy screening were performed. Logistic multiple regression was used to analyze related risk factors. RESULTS: The prevalence of DR were 15.8% and 41.2% in 2011 and 2013 respectively in the community. Compared with NDR group, age, family history of DM, duration of DM, fasting blood-glucose (FBG), 2h post-meal blood glucose (2hPG), hemoglobin A1c (HbA1c), total cholesterol (TC), serum creatinine (Scr), systolic blood pressure ( SBP ) , high - and low -density lipoprotein cholesterol ( HDL -C, LDL -C ) were statistically significant (P<0.05).The result of logistic regression showed that age, duration of DM, HbA1c, SBP and HDL-C were independent risk factors of DR. There were 31 new sufferers in 92 reexamined patients (33.7%) in 2013 and the main aetiological agent was poor glycemic control. CONCLUSION: The prevalence of DR in Fengyutan community was much higher than the other studies in northern China. It was primarily concerned with long duration of DM, poor glycemic control, inadequate concern with or even neglect of DM and the related oculopathy, hypertension and hyperlipidemia and so on.