CAJ | 학술논문

目的：探讨同型半胱氨酸对急性脑梗死诊断的临床价值。方法选择2012年2～8月在安康市人民医院确诊为急性脑梗死的患者150例设为实验组，选择同期进行体检且合格者150例设为健康对照组，测定同型半胱氨酸浓度，同时测定急性脑梗死相关血清化学指标超敏C-反应蛋白、总胆固醇含量，对结果进行统计分析。结果与健康对照组比较，急性脑梗死组血清同型半胱氨酸、超敏C-反应蛋白、总胆固醇均明显升高，差异具有统计学意义（P＜0．05），且轻、中、重型患者两两比较差异均有统计学差异（P＜0．05）；治疗前后同型半胱氨酸含量差异具有统计学意义（P＜0．05）。结论高同型半胱氨酸血症与急性脑梗死的诱发相关，同型半胱氨酸可作为判断急性脑梗死患者病情严重程度及预后的检测指标。
목적：탐토동형반광안산대급성뇌경사진단적림상개치。방법선택2012년2～8월재안강시인민의원학진위급성뇌경사적환자150례설위실험조，선택동기진행체검차합격자150례설위건강대조조，측정동형반광안산농도，동시측정급성뇌경사상관혈청화학지표초민C-반응단백、총담고순함량，대결과진행통계분석。결과여건강대조조비교，급성뇌경사조혈청동형반광안산、초민C-반응단백、총담고순균명현승고，차이구유통계학의의（P＜0．05），차경、중、중형환자량량비교차이균유통계학차이（P＜0．05）；치료전후동형반광안산함량차이구유통계학의의（P＜0．05）。결론고동형반광안산혈증여급성뇌경사적유발상관，동형반광안산가작위판단급성뇌경사환자병정엄중정도급예후적검측지표。
Objective To explore the clinical significance of homocystein in the diagnosis of acute cerebral in-farction (ACI) .Methods A total of 150 patients with ACI were enrolled as ACI group ,and 150 healthy subjects were enrolled as control group .Serum levels of homocystein ,high-sensitive C-reactive protein (hs-CRP) ,total choles-terol (TC) were detected and statistically analyzed .Results Compared with control group ,serum levels of homocys-tein ,hs-CRP and TC were all increased in ACI group (P<0 .05) ,and serum levels of theses indicators were with sta-tistical differences between patients with mild ,moderate and server ACI (P<0 .05) .Serum levels of homocystein in ACI group ,detected before and after treatment ,were with statistical difference (P<0 .05) .Conclusion Homocystein might be associated with the occurrence of ACI ,which could be used for judging severity of pathogenetic condition of patients with ACI .