CAJ | 학술논문

目的：观察芪夏消瘿汤和生白升血胶囊加减治疗甲状腺功能亢进症（简称甲亢）伴白细胞减少的临床疗效。方法选择甲亢合并白细胞减少66例，随机分成两组，治疗组40例，对照组26例。治疗组每日服用生白升血胶囊和芪夏消瘿汤加减中药水煎剂1付，连续服用14 d。对照组每日服用地榆生白片，3片／次，3次／日，连续服用14 d。服药前后进行有关项目对比。结果治疗组患者治疗后临床症状改善、白细胞总数上升38例，有效率95．0％，游离三碘甲状腺原氨酸为（9．60±1．08）pmol／L ，游离四碘甲状腺原氨酸（37．40±1．70）pmol／L ，甲状腺刺激激素为（0．11±1．11）uIU／mL。对照组白细胞总数上升21例，有效率80．8％，但甲状腺激素无变化，两组相比差异有统计学意义（P＜0．05）。结论芪夏消瘿汤和生白升血胶囊加减能升高白细胞，改善甲状腺激素水平。
목적：관찰기하소영탕화생백승혈효낭가감치료갑상선공능항진증（간칭갑항）반백세포감소적림상료효。방법선택갑항합병백세포감소66례，수궤분성량조，치료조40례，대조조26례。치료조매일복용생백승혈효낭화기하소영탕가감중약수전제1부，련속복용14 d。대조조매일복용지유생백편，3편／차，3차／일，련속복용14 d。복약전후진행유관항목대비。결과치료조환자치료후림상증상개선、백세포총수상승38례，유효솔95．0％，유리삼전갑상선원안산위（9．60±1．08）pmol／L ，유리사전갑상선원안산（37．40±1．70）pmol／L ，갑상선자격격소위（0．11±1．11）uIU／mL。대조조백세포총수상승21례，유효솔80．8％，단갑상선격소무변화，량조상비차이유통계학의의（P＜0．05）。결론기하소영탕화생백승혈효낭가감능승고백세포，개선갑상선격소수평。
Objective To observe the clinical effect of Qi Xia Xiao Ying Tang and Sheng Bai Sheng Xue cap-sule in treating hyperthyroidism with leukopenia .Methods A total of 40 hyperthyroidism patients with Leukopenia , enrolled as treatment group were given Qi Xia Xiao Ying Tang and Sheng Bai Sheng Xue Capsule .A total of 26 hy-perthyroidism patients with Leukopenia ,enrolled as control group ,were given Di Yu Sheng Bai tablets .Relative inde-xes were compared before and after treatment between the two groups .Results After treatment ,serum levels of free triiodothyronine ,free thyroxin decreased ,thyrotropic-stimulating hormone level increased ,and the differences with re-sults detected before treatment were significant (P<0 .05) ,and level of white blood cells was also increased and with significant difference (P<0 .05) .Conclusion Qi Xia Xiao Ying Tang and Sheng Bai Sheng Xue Capsule could effec-tively regulate serum levels of thyroid hormones in patents with hyperthyroidism and increasing the number of WBC .