重庆医学
重慶醫學
중경의학
CHONGQING MEDICAL JOURNAL
2014年
7期
823-825
,共3页
王明礼%刘建平%钟理%胡厚源%迟路湘%景涛%李永华%吕建峰%仝识非%宋治远
王明禮%劉建平%鐘理%鬍厚源%遲路湘%景濤%李永華%呂建峰%仝識非%宋治遠
왕명례%류건평%종리%호후원%지로상%경도%리영화%려건봉%동식비%송치원
血流储备分数 ,心肌%血管成形术 ,经腔 ,经皮冠状动脉%血管病变%meta分析
血流儲備分數 ,心肌%血管成形術 ,經腔 ,經皮冠狀動脈%血管病變%meta分析
혈류저비분수 ,심기%혈관성형술 ,경강 ,경피관상동맥%혈관병변%meta분석
fractional flow reserve,myocardial%angioplasty,transluminal,percutaneous coronary%vascular disease%meta-analysis
目的:系统地评价血流储备分数(FFR)与其他方法在多支血管病变患者中指导经皮冠状动脉介入治疗(PIC )的疗效。方法利用关键词“血流储备分数或者FFR、经皮冠状动脉介入治疗或者PCI、多支血管病变”的中英文检索中文数据库中国知网(CNKI)、万方和维普中文科技期刊数据库以及英文数据库Pubmed、EMBASE和Web of science中关于FFR指导PCI治疗多支血管病变的随机对照实验的文献。按照Jadad评分标准对纳入文献进行质量评价,利用Stata10.0进行荟萃分析。结果共有7篇英文文献,累计实验组2024人,对照组7284人纳入统计分析。与其他治疗方式相比,FFR指导PCI治疗多支血管病变发生心肌梗死的风险显著降低(RR=0.72,P=0.008);虽然患者出现死亡和主要心血管不良事件的风险也降低,但差异无统计学意义。结论 FFR指导PCI治疗多支血管病变是一种有效的治疗手段,但其是否适用于中国人群仍需要进一步验证。
目的:繫統地評價血流儲備分數(FFR)與其他方法在多支血管病變患者中指導經皮冠狀動脈介入治療(PIC )的療效。方法利用關鍵詞“血流儲備分數或者FFR、經皮冠狀動脈介入治療或者PCI、多支血管病變”的中英文檢索中文數據庫中國知網(CNKI)、萬方和維普中文科技期刊數據庫以及英文數據庫Pubmed、EMBASE和Web of science中關于FFR指導PCI治療多支血管病變的隨機對照實驗的文獻。按照Jadad評分標準對納入文獻進行質量評價,利用Stata10.0進行薈萃分析。結果共有7篇英文文獻,纍計實驗組2024人,對照組7284人納入統計分析。與其他治療方式相比,FFR指導PCI治療多支血管病變髮生心肌梗死的風險顯著降低(RR=0.72,P=0.008);雖然患者齣現死亡和主要心血管不良事件的風險也降低,但差異無統計學意義。結論 FFR指導PCI治療多支血管病變是一種有效的治療手段,但其是否適用于中國人群仍需要進一步驗證。
목적:계통지평개혈류저비분수(FFR)여기타방법재다지혈관병변환자중지도경피관상동맥개입치료(PIC )적료효。방법이용관건사“혈류저비분수혹자FFR、경피관상동맥개입치료혹자PCI、다지혈관병변”적중영문검색중문수거고중국지망(CNKI)、만방화유보중문과기기간수거고이급영문수거고Pubmed、EMBASE화Web of science중관우FFR지도PCI치료다지혈관병변적수궤대조실험적문헌。안조Jadad평분표준대납입문헌진행질량평개,이용Stata10.0진행회췌분석。결과공유7편영문문헌,루계실험조2024인,대조조7284인납입통계분석。여기타치료방식상비,FFR지도PCI치료다지혈관병변발생심기경사적풍험현저강저(RR=0.72,P=0.008);수연환자출현사망화주요심혈관불량사건적풍험야강저,단차이무통계학의의。결론 FFR지도PCI치료다지혈관병변시일충유효적치료수단,단기시부괄용우중국인군잉수요진일보험증。
Objective To systematically evaluate the clinical outcomes of patients with multivessel diseases treated by fractional flow reserve (FFR) guided percutaneous coronary intervention (PCI) or other forms of treatment .Methods Some keywords inclu-ding FFR or fractional flow reserve ,percutaneous coronary intervention or PCI ,multivessel coronary artery disease were used to search randomized control trails(RCT) ,which compared outcomes of patients with multivessel disease treated by FFR guided PCI with other forms of treatment ,in Chinese and English database including CNKI ,VIP ,Wanfang ,Pubmed ,EMBASE and the web of science .The quality of included studies was evaluated by Jadad quality score and all the data was analyzed by stata 10 .0 .Results A total of 7 english literatures accumulating 2024 cases in experimental group and 7 284 cases in control group were included in this study .Compared with other forms of treatment ,patients with multivessel diseases treated by FFR-guided PCI had significantly low-er risk of myocardial infarction (RR=0 .72 ,P=0 .008) .Although the risk of death and major adverse cardiovascular events were al-so be reduced ,there were no statistically significant difference .Conclusion FFR-guided PCI is an effective treatment for multivessel disease ,but it is still needs further verification for the application in Chinese population .