中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2014年
9期
57-58,59
,共3页
肺部感染%病原菌%医院感染%耐药性
肺部感染%病原菌%醫院感染%耐藥性
폐부감염%병원균%의원감염%내약성
Pulmonary infection%Pathogens%Nosocomial infections%Drug resistance
目的：了解肺部感染病原菌的分布及耐药性等病原学特点，为临床合理选用抗菌药物提供依据。方法：收集并回顾性分析笔者所在医院符合肺部感染治疗标准的360例感染患者临床资料，进行病原菌培养和药物敏感试验并对结果进行分析。结果：360例感染患者共培养出菌株210株，检出率为58.3%，病原菌中以革兰氏阴性杆菌感染为主；主要以肺炎克雷伯菌、大肠埃希菌和鲍曼不动杆菌为主，分别为22.9%、19.1%、13.8%；在革兰氏阳性菌感染中以葡萄球菌和肺炎链球菌为主，分别为6.2%、3.8%；真菌感染占12.8%，主要为白假丝酵母菌。且革兰氏阴性杆菌产ESBLs的耐药性明显高于非产ESBLs的耐药性。结论：肺部感染需要监测病原菌的种类和药敏变化，真菌感染率上升，多重耐药菌增加，临床医师需密切关注分离菌的变迁及耐药情况，合理使用抗菌药物。
目的：瞭解肺部感染病原菌的分佈及耐藥性等病原學特點，為臨床閤理選用抗菌藥物提供依據。方法：收集併迴顧性分析筆者所在醫院符閤肺部感染治療標準的360例感染患者臨床資料，進行病原菌培養和藥物敏感試驗併對結果進行分析。結果：360例感染患者共培養齣菌株210株，檢齣率為58.3%，病原菌中以革蘭氏陰性桿菌感染為主；主要以肺炎剋雷伯菌、大腸埃希菌和鮑曼不動桿菌為主，分彆為22.9%、19.1%、13.8%；在革蘭氏暘性菌感染中以葡萄毬菌和肺炎鏈毬菌為主，分彆為6.2%、3.8%；真菌感染佔12.8%，主要為白假絲酵母菌。且革蘭氏陰性桿菌產ESBLs的耐藥性明顯高于非產ESBLs的耐藥性。結論：肺部感染需要鑑測病原菌的種類和藥敏變化，真菌感染率上升，多重耐藥菌增加，臨床醫師需密切關註分離菌的變遷及耐藥情況，閤理使用抗菌藥物。
목적：료해폐부감염병원균적분포급내약성등병원학특점，위림상합리선용항균약물제공의거。방법：수집병회고성분석필자소재의원부합폐부감염치료표준적360례감염환자림상자료，진행병원균배양화약물민감시험병대결과진행분석。결과：360례감염환자공배양출균주210주，검출솔위58.3%，병원균중이혁란씨음성간균감염위주；주요이폐염극뢰백균、대장애희균화포만불동간균위주，분별위22.9%、19.1%、13.8%；재혁란씨양성균감염중이포도구균화폐염련구균위주，분별위6.2%、3.8%；진균감염점12.8%，주요위백가사효모균。차혁란씨음성간균산ESBLs적내약성명현고우비산ESBLs적내약성。결론：폐부감염수요감측병원균적충류화약민변화，진균감염솔상승，다중내약균증가，림상의사수밀절관주분리균적변천급내약정황，합리사용항균약물。
Objective:To investigate the pathogenic bacteria distribution and drug resistance of pulmonary infection,in order to provide basis for clinical reasonable use of antimicrobial drugs.Method:Collected and retrospectively analyzed the clinical data of 360 cases of infection with the standard treatment of patients were pulmonary infection,the results of pathogenic bacteria culture and drug sensitivity tests were analyzed.Result:360 cases of infected patients were cultured 210 strains,the positive rate was 58.3%,the pathogenic bacteria were gram-negative bacilli infection;mainly in klebsiella pneumoniae,escherichia coli and bauman Acinetobacter,respectively 22.9%,19.1%,13.8%;Staphylococcus aureus and streptococcus pneumoniae in Gram-positive bacteria infection, were 6.2%,3.8%;Fungal infection accounted for 12.8%,mainly for candida albicans.Drug resistance of gram-negative bacilli and drug resistance of ESBLs was significantly higher than that of ESBLs.Conclusion:Distribution and drug resistance of pathogenic bacteria to monitor changes in pulmonary infection,fungal infection rates rose,multiple drug-resistant bacteria increased,and the clinician should pay close attention to the changes and separation of drug-resistant bacteria,and rational use of antimicrobial agents.
