重庆医学
重慶醫學
중경의학
CHONGQING MEDICAL JOURNAL
2014年
8期
932-934
,共3页
子痫%孕龄%胎盘功能不全%母婴结局
子癇%孕齡%胎盤功能不全%母嬰結跼
자간%잉령%태반공능불전%모영결국
eclampsia%gestational age%placental insufficiency%maternal and neonatal outcomes
目的:探讨早发型重度子痫前期不同孕龄与母婴结局的关系。方法选择70例早发型重度子痫前期患者,根据发病时孕周将其分为28~31周组(33例)、32~34周组(37例)。比较两组患者临床资料、并发症及围生儿结局。结果28~31周组终止妊娠时间(31.8±0.9)周、期待治疗时间(12.4±4.1)d、新生儿体质量增加量(493.5±20.3)g与32~34周组[(33.5±1.2)周、(8.1±3.9) d、(302.2±18.6)g ]比较差异有统计学意义( P<0.05);28~31周组期待治疗时间大于或等于1周患者的围生儿结局明显好于期待治疗时间小于1周者( P<0.05);28~31周组围生儿病死率(27.3%)、新生儿监护病房(N IC U )入住率(36.4%)均明显高于32~34周组(8.1%、13.5%)( P<0.05);28~31周组并发症中肾功能异常(51.5%)、H EL L P综合征(6.1%)、胎盘功能不良(45.5%)的比例与32~34周组(21.6%、24.3%、21.6%)比较差异有统计学意义( P<0.05)。结论早发型重度子痫前期会导致围生儿病死率高,N IC U入住率高,容易发生并发症。
目的:探討早髮型重度子癇前期不同孕齡與母嬰結跼的關繫。方法選擇70例早髮型重度子癇前期患者,根據髮病時孕週將其分為28~31週組(33例)、32~34週組(37例)。比較兩組患者臨床資料、併髮癥及圍生兒結跼。結果28~31週組終止妊娠時間(31.8±0.9)週、期待治療時間(12.4±4.1)d、新生兒體質量增加量(493.5±20.3)g與32~34週組[(33.5±1.2)週、(8.1±3.9) d、(302.2±18.6)g ]比較差異有統計學意義( P<0.05);28~31週組期待治療時間大于或等于1週患者的圍生兒結跼明顯好于期待治療時間小于1週者( P<0.05);28~31週組圍生兒病死率(27.3%)、新生兒鑑護病房(N IC U )入住率(36.4%)均明顯高于32~34週組(8.1%、13.5%)( P<0.05);28~31週組併髮癥中腎功能異常(51.5%)、H EL L P綜閤徵(6.1%)、胎盤功能不良(45.5%)的比例與32~34週組(21.6%、24.3%、21.6%)比較差異有統計學意義( P<0.05)。結論早髮型重度子癇前期會導緻圍生兒病死率高,N IC U入住率高,容易髮生併髮癥。
목적:탐토조발형중도자간전기불동잉령여모영결국적관계。방법선택70례조발형중도자간전기환자,근거발병시잉주장기분위28~31주조(33례)、32~34주조(37례)。비교량조환자림상자료、병발증급위생인결국。결과28~31주조종지임신시간(31.8±0.9)주、기대치료시간(12.4±4.1)d、신생인체질량증가량(493.5±20.3)g여32~34주조[(33.5±1.2)주、(8.1±3.9) d、(302.2±18.6)g ]비교차이유통계학의의( P<0.05);28~31주조기대치료시간대우혹등우1주환자적위생인결국명현호우기대치료시간소우1주자( P<0.05);28~31주조위생인병사솔(27.3%)、신생인감호병방(N IC U )입주솔(36.4%)균명현고우32~34주조(8.1%、13.5%)( P<0.05);28~31주조병발증중신공능이상(51.5%)、H EL L P종합정(6.1%)、태반공능불량(45.5%)적비례여32~34주조(21.6%、24.3%、21.6%)비교차이유통계학의의( P<0.05)。결론조발형중도자간전기회도치위생인병사솔고,N IC U입주솔고,용역발생병발증。
Objective To investigate affect of maternal and neonatal outcomes of pregnant women with early onset severe pre-eclampsia in different gestational age .Methods 70 pregnant women with early onset severe preeclampsia were selected to divided into 28-31 weeks group(n=33) ,32-34 weeks group(n=37) ,then the clinical conditions ,the complications of pregnant women and the perinatal outcomes were compared .Results The termination of pregnancy time (31 .8 ± 0 .9)weeks ,expectant treatment time(12 .4 ± 4 .1)d ,neonatal weight gain (493 .5 ± 20 .3)g of 28 -31 weeks group had significant difference with 32 -34 weeks group[(33 .5 ± 1 .2)weeks ,(8 .1 ± 3 .9)d ,(302 .2 ± 18 .6)g](P<0 .05) .Perinatal outcomes of expectant treatment time over one week was significantly better than expectant treatment time under one week (P<0 .05) .Perinatal mortality (27 .3% ) ,Neonatal in-tensive care unit(NICU ) occupancy rate (36 .4% ) of 28 -31 weeks group were significantly higher than 32 -34 weeks group (8 .1% ,13 .5% )(P< 0 .05).The proportion of renal dysfunction(51 .5% ),HELLP syndrome(6 .1% ),placental dysfunction (45 .5% ) in 28-31 weeks group had significant difference with 32-34 weeks group(21 .6% ,24 .3% ,21 .6% )(P<0 .05) .Conclu-sion Early onset severe preeclampsia can cause high perinatal mortality ,high NICU occupancy ,and prone to complications ,and positive treatment should be taken according to the condition .