内蒙古民族大学学报：自然科学版
內矇古民族大學學報：自然科學版
내몽고민족대학학보：자연과학판
Journal of Inner Mongolia University for the Nationalities(Natural Sciences)
2012年
1期
68-70
,共3页
包春生%额尔敦朝鲁%乌云苏热古格
包春生%額爾敦朝魯%烏雲囌熱古格
포춘생%액이돈조로%오운소열고격
周围神经损伤%额日敦乌日勒%坐骨神经功能指数
週圍神經損傷%額日敦烏日勒%坐骨神經功能指數
주위신경손상%액일돈오일륵%좌골신경공능지수
Peripheral nerve injury%Erdunwurle%Sciatic nerve functional index
目的：通过实验观察额日敦乌日勒对坐骨神经损伤的治疗效果,为临床治疗提供依据.方法：Wistar大鼠20只随机分组为模型组和给药组.用止血钳钳夹坐骨神经,造模后1d、3d、5d、7d、14d、21d、24d、28d测定热缩足反射潜伏期（TWL）和造模后1周、4周通过测定坐骨神经功能指数（SFI）、坐骨神经传导速度（NCV）来观察额日敦乌日勒对坐骨神经功能恢复的影响.结果：坐骨神经功能指数在造模后1周,给药组明显优于模型组（P〈0.05.）热缩足反射潜伏期（TWL）在造模后第24d两组比较有显著性差异（P〈0.05）.造模后1周和4周两组坐骨神经传导速度比较有明显差异,给药组明显优于模型组（P〈0.05.）结论：蒙药额日敦乌日勒对大鼠坐骨神经功能恢复有明显的促进作用.
目的：通過實驗觀察額日敦烏日勒對坐骨神經損傷的治療效果,為臨床治療提供依據.方法：Wistar大鼠20隻隨機分組為模型組和給藥組.用止血鉗鉗夾坐骨神經,造模後1d、3d、5d、7d、14d、21d、24d、28d測定熱縮足反射潛伏期（TWL）和造模後1週、4週通過測定坐骨神經功能指數（SFI）、坐骨神經傳導速度（NCV）來觀察額日敦烏日勒對坐骨神經功能恢複的影響.結果：坐骨神經功能指數在造模後1週,給藥組明顯優于模型組（P〈0.05.）熱縮足反射潛伏期（TWL）在造模後第24d兩組比較有顯著性差異（P〈0.05）.造模後1週和4週兩組坐骨神經傳導速度比較有明顯差異,給藥組明顯優于模型組（P〈0.05.）結論：矇藥額日敦烏日勒對大鼠坐骨神經功能恢複有明顯的促進作用.
목적：통과실험관찰액일돈오일륵대좌골신경손상적치료효과,위림상치료제공의거.방법：Wistar대서20지수궤분조위모형조화급약조.용지혈겸겸협좌골신경,조모후1d、3d、5d、7d、14d、21d、24d、28d측정열축족반사잠복기（TWL）화조모후1주、4주통과측정좌골신경공능지수（SFI）、좌골신경전도속도（NCV）래관찰액일돈오일륵대좌골신경공능회복적영향.결과：좌골신경공능지수재조모후1주,급약조명현우우모형조（P〈0.05.）열축족반사잠복기（TWL）재조모후제24d량조비교유현저성차이（P〈0.05）.조모후1주화4주량조좌골신경전도속도비교유명현차이,급약조명현우우모형조（P〈0.05.）결론：몽약액일돈오일륵대대서좌골신경공능회복유명현적촉진작용.
Objective:To provide the basis for the clinical application of Mongolian Medicine Erdunwurle by observing the therapeutic effect on the functional restoration of injured sciatic nerve in rats.Methods: 20 female Wistar rats were randomly divided into model and treatment groups.The sciatic nerve was clamped by forceps hamostatic,TWL was determined at 1d,3d,5d,7d,14d,21d,24d,28d after modeling and sciatic function index(SFI) and nerve conduction velocity(NCV) were detected at 1st week and 4th week to observe the effect of Erdunwurle on the functional restoration of injured sciatic nerve.Results: The functional restoration of rats in treatment group was obviously better than that in model group(P 0.05) after modeling.The TWL between two groups had significant difference at 24d after modeling.The NCV between two groups had significant difference at 1st week and 4th week after modeling.NCV of rats in treatment group was better than that in model group(P0.05).Conclusion: Mongolian Medicine Erdunwurle is capable of obviously promoting the functional recovery after sciatic nerve injury in rats.
