CAJ | 학술논문

类鼻疽伯克霍尔德菌（Burkholderia pseudomallei）是引起主要发生在东南亚和澳大利亚北部的一种人兽共患病类鼻疽的潜在病原。明确该疾病致病机理及其宿主与病原的互作将加强对该条件致病菌的发病机制的理解。本研究从影响细菌致病性的毒力因子和病原与宿主互作两个方面阐述类鼻疽伯克霍德尔菌的致病机理，为该菌的有效控制提供可能的机制。
류비저백극곽이덕균（Burkholderia pseudomallei）시인기주요발생재동남아화오대리아북부적일충인수공환병류비저적잠재병원。명학해질병치병궤리급기숙주여병원적호작장가강대해조건치병균적발병궤제적리해。본연구종영향세균치병성적독력인자화병원여숙주호작량개방면천술류비저백극곽덕이균적치병궤리，위해균적유효공제제공가능적궤제。
Burkholderia pseudomallei is a potential bioterror agent and the causative agent of melioidosis, a se- vere disease that is endemic in areas of Southeast Asia and Northern Australia. Studying how the disease is ac- quired and the host-pathogen interactions involved will underpin understanding of the bacteria, This review presents an overview focused on current knowledge of putative virulence factors and the host-pathogen interac- tions,led to understanding of the infection process of Burkholderia pseudomallei and effective control strategy.