CAJ | 학술논문

麝是古北界的特有种和我国一级保护动物，具有相当重要的经济价值和物种保护价值．幼麝的高死亡率，特别是由腹泻或肠炎所引起的死亡已经严重地影响着中国养麝业的发展．从甘肃兴隆山养麝场死于消化道疾病的高山麝（？dos—chuschrysogaster）的肠道内容物中分离出了病原性的肠杆菌．基于形态学、生理生化特征及16SrRNA基因序列的种系遗传学综合分析鉴定其为阿尔伯蒂埃希氏杆菌（Escherichiaalbertii）．对该茵进行抗生素敏感性检测，结果表明，其对不同的抗生素有不同的敏感性，这可能是麝长期经受少数几种固定的抗生素（如青霉素、四环素）治疗，细菌产生抗性而使抗生素失效所致．建议麝场定期对肠杆菌进行分离、鉴定，选用具有针对性的菌株制作菌苗，配以敏感的药物、中草药添加剂和良好的卫生措施，以控制埃希氏杆菌疾病的发生．
사시고북계적특유충화아국일급보호동물，구유상당중요적경제개치화물충보호개치．유사적고사망솔，특별시유복사혹장염소인기적사망이경엄중지영향착중국양사업적발전．종감숙흥륭산양사장사우소화도질병적고산사（？dos—chuschrysogaster）적장도내용물중분리출료병원성적장간균．기우형태학、생리생화특정급16SrRNA기인서렬적충계유전학종합분석감정기위아이백체애희씨간균（Escherichiaalbertii）．대해인진행항생소민감성검측，결과표명，기대불동적항생소유불동적민감성，저가능시사장기경수소수궤충고정적항생소（여청매소、사배소）치료，세균산생항성이사항생소실효소치．건의사장정기대장간균진행분리、감정，선용구유침대성적균주제작균묘，배이민감적약물、중초약첨가제화량호적위생조시，이공제애희씨간균질병적발생．
Musk deer (Mosch, us spp. ) are peculiar to the Palearctic and of considerable value worldwide. The high mortality-rate of fawns, especially caused by diarrhea or enteritis, has severely hindered the de- velopment of Chinese musk deer farming. In this study, two strains of pathogenic Enterobacteriaceae were isolated from the intestinal contents of an Alpine Musk Deer (Moschus chrysogaster) which died from digestive diseases at Xinglongshan Musk Deer Farm, Gansu Province,China. They were identified as strains of Escherichia albertii, based on an integrated analysis of morphological, physiological and bio- chemical characteristics as well as phylogenetics of genetic sequences 16SrRNA. The results of antibiotic sensitivity tests showed that the sensitivities of the bacteria to different antibiotics varied. This might have resulted from the animal's long treatment for colibacillosis by a fixed set of antlbiotics,including penicillin G and tetracycline,which might have lost efficacy because of bacterial resistance. A feasible ap- proach to controlling colibacillosis in future would be alternative use of antibiotics combined with other preventive measures.