CAJ | 학술논문

华支睾吸虫病是主要流行于东亚地区的一种由华支睾吸虫所引起的寄生虫病，传统的病原学诊断方法有着明显的局限和弊病，免疫学和分子生物学的发展为诊断提供了新的途径。随着对诊断抗原、抗体研究的深入以及诊断方法的改进，华支睾吸虫病诊断的敏感性和特异性不断提高。该文着重对华支睾吸虫病的免疫诊断尤其是诊断抗原的研究进展简要综述。
화지고흡충병시주요류행우동아지구적일충유화지고흡충소인기적기생충병，전통적병원학진단방법유착명현적국한화폐병，면역학화분자생물학적발전위진단제공료신적도경。수착대진단항원、항체연구적심입이급진단방법적개진，화지고흡충병진단적민감성화특이성불단제고。해문착중대화지고흡충병적면역진단우기시진단항원적연구진전간요종술。
Clonorchiasis is a parasitic disease caused by Clonorchis sinensis and mainly popular in East Asia. The traditional aetiological diagnosis methods have obvious limitations and defects. The development of immunology and molecular biology has provided a new way for the diagnosis. Following with the in-depth study of diagnostic antigen, antibody and improvement of diagnosis methods, the sensitivity and specificity for diagnosing clonorchiasis was continuously improved. This paper emphatically summarized immunologic diagnosis of clonorchiasis, especially the progress in diagnostic antigens.