大理学院学报：综合版
大理學院學報：綜閤版
대이학원학보：종합판
Journal of Dali University
2012年
12期
20-23
,共4页
邓仪昊%何红云%王勇
鄧儀昊%何紅雲%王勇
산의호%하홍운%왕용
结核分枝杆菌%ESX-1分泌系统%ESAT-6%CFP-10
結覈分枝桿菌%ESX-1分泌繫統%ESAT-6%CFP-10
결핵분지간균%ESX-1분비계통%ESAT-6%CFP-10
Mycobacterium tuberculosis%ESX-1 secretion system%ESAT-6%CFP-10
目的：综述结核分枝杆菌ESX-1分泌系统的组成及其组分的作用。方法：检索并查阅结核分枝杆菌ESX-1分泌系统相关的文献，并进行9-3纳总结。结果：ESX-1系统是以分泌ESAT-6及CFP-10为特征的分泌系统，包括编码基因及十余种分泌调节基因。结论：结核分枝杆菌毒力分子ESAT-6及CFP-10的分泌是多种相关编码基因共同作用的结果。
目的：綜述結覈分枝桿菌ESX-1分泌繫統的組成及其組分的作用。方法：檢索併查閱結覈分枝桿菌ESX-1分泌繫統相關的文獻，併進行9-3納總結。結果：ESX-1繫統是以分泌ESAT-6及CFP-10為特徵的分泌繫統，包括編碼基因及十餘種分泌調節基因。結論：結覈分枝桿菌毒力分子ESAT-6及CFP-10的分泌是多種相關編碼基因共同作用的結果。
목적：종술결핵분지간균ESX-1분비계통적조성급기조분적작용。방법：검색병사열결핵분지간균ESX-1분비계통상관적문헌，병진행9-3납총결。결과：ESX-1계통시이분비ESAT-6급CFP-10위특정적분비계통，포괄편마기인급십여충분비조절기인。결론：결핵분지간균독력분자ESAT-6급CFP-10적분비시다충상관편마기인공동작용적결과。
Objective: To review components and their functions of ESAT-6 secretion system-1 (ESX-1) of Mycobacterium tuberculosis. Methods: Consult and summarize related reference material about ESX-1 secretion system of Mycobacterium tuberculosis. Results: ESX-1 secretion system is characterized by secretion of ESAT-6 and CFP-IO, including coding genes and more than ten secretive regulator genes. Conclusion: The secretions of virulence factor of ESAT-6 and CFP-10 in Mycobacterium tuberculosis were controlled by multiple related encoding genes.
