精细与专用化学品
精細與專用化學品
정세여전용화학품
FINE AND SPECIALTY CHEMICALS
2013年
5期
37-39
,共3页
阿昔洛韦%N-2,9-二乙酰基鸟嘌呤%1,4-二乙酰氧基-2-氧杂丁烷
阿昔洛韋%N-2,9-二乙酰基鳥嘌呤%1,4-二乙酰氧基-2-氧雜丁烷
아석락위%N-2,9-이을선기조표령%1,4-이을선양기-2-양잡정완
以N-2,9-二乙酰基鸟嘌呤和1,4-二乙酰氧基-2-氧杂丁烷为原料,经缩合反应制备阿昔洛韦有关物质2-[[2-(acetylamino)-6-oxo-1,6-dihydro-7H-purin-7-yl] methoxyl] ethyl acetate(化合物2),化合物2经过水解反应可得到阿昔洛韦有关物质2-a-mino-7-[(2-hydroxyehoxy) methyl]-1,7-dihydro-6 H-purin-6-one(化合物3).
以N-2,9-二乙酰基鳥嘌呤和1,4-二乙酰氧基-2-氧雜丁烷為原料,經縮閤反應製備阿昔洛韋有關物質2-[[2-(acetylamino)-6-oxo-1,6-dihydro-7H-purin-7-yl] methoxyl] ethyl acetate(化閤物2),化閤物2經過水解反應可得到阿昔洛韋有關物質2-a-mino-7-[(2-hydroxyehoxy) methyl]-1,7-dihydro-6 H-purin-6-one(化閤物3).
이N-2,9-이을선기조표령화1,4-이을선양기-2-양잡정완위원료,경축합반응제비아석락위유관물질2-[[2-(acetylamino)-6-oxo-1,6-dihydro-7H-purin-7-yl] methoxyl] ethyl acetate(화합물2),화합물2경과수해반응가득도아석락위유관물질2-a-mino-7-[(2-hydroxyehoxy) methyl]-1,7-dihydro-6 H-purin-6-one(화합물3).
