中国医药
中國醫藥
중국의약
CHINA MEDICINE
2013年
3期
342-344
,共3页
李秋俐%王磊%解恒革%尹世敏
李鞦俐%王磊%解恆革%尹世敏
리추리%왕뢰%해항혁%윤세민
非痴呆性血管性认知功能障碍%诊断标准%记忆功能
非癡呆性血管性認知功能障礙%診斷標準%記憶功能
비치태성혈관성인지공능장애%진단표준%기억공능
Non-dementia vascular cognitive impairment%Diagnosis criterion%Memory function
目的 探讨非痴呆性血管性认知功能障碍(VCIND)患者记忆功能特点.方法 选取VCIND患者21例(VCIMD组)、脑血管病无认知障碍(CVD)患者15例(CVD组)、对照组22例.入选对象均测查记忆力、注意力、语言能力,且采用改良的诊断标准进行诊断.结果 VCIND组患者85.7％(18/21)有记忆功能减退的主诉,明显多于CVD组[26.4％ (4/15)]和对照组[36.4％ (8/22)] (P ＜0.05).简易智力状态检查:对照组(28.0±1.3)分,CVD组(28.5 ± 10)分,VCIND组(26.4±1.8)分；阿尔茨海默病评价量表-认知分表:对照组(5.1±2.6)分,CVD组(5.7±2.2)分,VCIND组(11.5±4.4)分；语言流畅性测验:对照组(16.0±2.6)分,CVD组(17.3±1.2)分,VCIND组(12.8±3.0)分.单词回忆:对照组(3.0±1.2)分,CVD组(3.1±1.2)分,VCIND组(5.3±2.0)分.VCIND组总体认知功能、记忆功能、语言功能较CVD组和对照组均明显衰退(均P ＜0.05).结论 绝大多数VCIND患者存在近记忆力损害,词语记忆困难突出,且大多数以记忆力下降为首发症状.
目的 探討非癡呆性血管性認知功能障礙(VCIND)患者記憶功能特點.方法 選取VCIND患者21例(VCIMD組)、腦血管病無認知障礙(CVD)患者15例(CVD組)、對照組22例.入選對象均測查記憶力、註意力、語言能力,且採用改良的診斷標準進行診斷.結果 VCIND組患者85.7％(18/21)有記憶功能減退的主訴,明顯多于CVD組[26.4％ (4/15)]和對照組[36.4％ (8/22)] (P ＜0.05).簡易智力狀態檢查:對照組(28.0±1.3)分,CVD組(28.5 ± 10)分,VCIND組(26.4±1.8)分；阿爾茨海默病評價量錶-認知分錶:對照組(5.1±2.6)分,CVD組(5.7±2.2)分,VCIND組(11.5±4.4)分；語言流暢性測驗:對照組(16.0±2.6)分,CVD組(17.3±1.2)分,VCIND組(12.8±3.0)分.單詞迴憶:對照組(3.0±1.2)分,CVD組(3.1±1.2)分,VCIND組(5.3±2.0)分.VCIND組總體認知功能、記憶功能、語言功能較CVD組和對照組均明顯衰退(均P ＜0.05).結論 絕大多數VCIND患者存在近記憶力損害,詞語記憶睏難突齣,且大多數以記憶力下降為首髮癥狀.
목적 탐토비치태성혈관성인지공능장애(VCIND)환자기억공능특점.방법 선취VCIND환자21례(VCIMD조)、뇌혈관병무인지장애(CVD)환자15례(CVD조)、대조조22례.입선대상균측사기억력、주의력、어언능력,차채용개량적진단표준진행진단.결과 VCIND조환자85.7％(18/21)유기억공능감퇴적주소,명현다우CVD조[26.4％ (4/15)]화대조조[36.4％ (8/22)] (P ＜0.05).간역지력상태검사:대조조(28.0±1.3)분,CVD조(28.5 ± 10)분,VCIND조(26.4±1.8)분；아이자해묵병평개량표-인지분표:대조조(5.1±2.6)분,CVD조(5.7±2.2)분,VCIND조(11.5±4.4)분；어언류창성측험:대조조(16.0±2.6)분,CVD조(17.3±1.2)분,VCIND조(12.8±3.0)분.단사회억:대조조(3.0±1.2)분,CVD조(3.1±1.2)분,VCIND조(5.3±2.0)분.VCIND조총체인지공능、기억공능、어언공능교CVD조화대조조균명현쇠퇴(균P ＜0.05).결론 절대다수VCIND환자존재근기억력손해,사어기억곤난돌출,차대다수이기억력하강위수발증상.
Objective To discuss the memory function characteristics of the patients with vascular cognitive impairment no dementia (VCIND).Methods Twenty-one patients of VCIND group,15 patients of cerebrovascular disease (CVD) group and 22 patients of normal control group were selected in this study.All the selected subjects received the medical examination of memory,attention,language ability and the brain MRI scan,and then they were diagnosed by the improved criteria.Results 85.7 percent patients of VCIND group complained of the decline in the memory function,whereas the difference between CVD group and control group was not significant.The general cognition,memory and language functions of patients in the VCIND group had significantly more decline than those in CVD groups [(11.5 ± 4.4) scores vs (5.7 ± 2.2) scores,(5.3 ± 2.0) scores vs (3.1 ± 1.2) scores,(12.8 ±3.0)scores vs(17.3 ±l.2)scores,all P＜0.05].Conclusion Most patients with VCIND have memory impairment,especially have the difficulty in the memory of words and expressions and have the initial symptom of memory impairment.
