白血病·淋巴瘤
白血病·淋巴瘤
백혈병·림파류
JOURNAL OF LEUKEMIA & LYMPHOMA
2014年
3期
166-168,188
,共4页
淋巴瘤,非霍奇金%胃肠道淋巴瘤%T细胞淋巴瘤%B细胞淋巴瘤
淋巴瘤,非霍奇金%胃腸道淋巴瘤%T細胞淋巴瘤%B細胞淋巴瘤
림파류,비곽기금%위장도림파류%T세포림파류%B세포림파류
Lymphoma,non-Hodgkin%Gastrointestinal lymphoma%T-cell lymphoma%B-cell lymphoma
目的 了解不同细胞来源原发性胃肠道非霍奇金淋巴瘤(PGINHL)的临床特征、诊断治疗及预后.方法 回顾性分析明确诊断的51例PGINHL病例资料,分析B细胞来源与T细胞来源的PGINHL的临床表现、诊断治疗,并随访其预后.结果 51例PGINHL患者中位年龄56岁,男女比例为1.44∶1,B细胞来源35例(68.7％),T细胞来源16例(31.3％).T细胞淋巴瘤较B细胞淋巴瘤患者便血、腹泻、盗汗发生率高(P＜0.05);T细胞淋巴瘤较B细胞淋巴瘤患者总体预后差.黏膜相关组织淋巴瘤(MALT)预后最好,剔除MALT后,T细胞淋巴瘤与B细胞淋巴瘤患者预后差异无统计学意义(P＞0.05).结论 在PGINHL患者中,B细胞来源淋巴瘤比例高,且预后好于T细胞淋巴瘤.
目的 瞭解不同細胞來源原髮性胃腸道非霍奇金淋巴瘤(PGINHL)的臨床特徵、診斷治療及預後.方法 迴顧性分析明確診斷的51例PGINHL病例資料,分析B細胞來源與T細胞來源的PGINHL的臨床錶現、診斷治療,併隨訪其預後.結果 51例PGINHL患者中位年齡56歲,男女比例為1.44∶1,B細胞來源35例(68.7％),T細胞來源16例(31.3％).T細胞淋巴瘤較B細胞淋巴瘤患者便血、腹瀉、盜汗髮生率高(P＜0.05);T細胞淋巴瘤較B細胞淋巴瘤患者總體預後差.黏膜相關組織淋巴瘤(MALT)預後最好,剔除MALT後,T細胞淋巴瘤與B細胞淋巴瘤患者預後差異無統計學意義(P＞0.05).結論 在PGINHL患者中,B細胞來源淋巴瘤比例高,且預後好于T細胞淋巴瘤.
목적 료해불동세포래원원발성위장도비곽기금림파류(PGINHL)적림상특정、진단치료급예후.방법 회고성분석명학진단적51례PGINHL병례자료,분석B세포래원여T세포래원적PGINHL적림상표현、진단치료,병수방기예후.결과 51례PGINHL환자중위년령56세,남녀비례위1.44∶1,B세포래원35례(68.7％),T세포래원16례(31.3％).T세포림파류교B세포림파류환자편혈、복사、도한발생솔고(P＜0.05);T세포림파류교B세포림파류환자총체예후차.점막상관조직림파류(MALT)예후최호,척제MALT후,T세포림파류여B세포림파류환자예후차이무통계학의의(P＞0.05).결론 재PGINHL환자중,B세포래원림파류비례고,차예후호우T세포림파류.
Objective To understand the clinical characteristics and treatment outcomes of primary gastrointestinal non-Hodgkin lymphomas (PGINHL) and analyze the differences between T-cell and B-cell lymphomas.Methods.The characteristics of 51 PGINHL patients were analyzed regarding to their clinical manifestations,diagnosis,treatments and outcomes.Results 51 cases of PGINHL meeting the WHO(2008) criteria were identified.The median age of the patients at the time of diagnosis was 56 years old and the male ∶ female ratio was 1.44∶1,35 cases (68.7 ％) had B-lineage and 16 cases (31.3 ％) had T-cell lineage lymphomas.Compared to those with B-cell lymphoma,patients with T-cell lymphoma presented with a greater incidence of such symptoms as hematochezia,diarrhea and night sweating (P ＜ 0.05).After eliminating MALT lymphoma,prognosis of T-cell lymphoma and B-cell lymphoma had no significant difference.Conclusion In PGINHL cases,B-cell lymphomas appeare to be more common and have better prognosis than T-cell lymphomas.
