CAJ | 학술논문

　　目的：此次临床研究主要对曲美他嗪联合稳心颗粒治疗不稳定型心绞痛的临床效果进行观察和分析。方法：此次临床研究主要以我院教学医院在2009年3月份到2012年3月份的100例不稳定型心绞痛患者为研究对象，采用随机分配的原则，将100例患者随机分成对照组和实验组，每个组别各50例，对照组患者在治疗方法上主要采用曲美他嗪进行治疗，而实验组患者则采用曲美他嗪联合稳心颗粒进行治疗。两组患者经过14天的治疗后，对两组患者的临床效果、药物的不良反应以及发作情况进行观察和比较。结果：经过临床研究结果显示，实验组采用曲美他嗪联合稳心颗粒进行治疗，总有效率明显高于对照组患者，发作次数明显少于对照组，两组患者在临床效果以及发作情况的比较上，具有显著差异性，存在统计学意义，P<0.05；在药物不良反应的发生率比较上，两组患者均没有显著差异性，不具有统计学意义，P>0.05。结论：经临床研究表明，采用曲美他嗪联合稳心颗粒对不稳定型心绞痛患者进行治疗，具有显著的临床效果，不良反应较少，具有较高的临床应用价值以及安全性，值得推广和普及。
　　목적：차차림상연구주요대곡미타진연합은심과립치료불은정형심교통적림상효과진행관찰화분석。방법：차차림상연구주요이아원교학의원재2009년3월빈도2012년3월빈적100례불은정형심교통환자위연구대상，채용수궤분배적원칙，장100례환자수궤분성대조조화실험조，매개조별각50례，대조조환자재치료방법상주요채용곡미타진진행치료，이실험조환자칙채용곡미타진연합은심과립진행치료。량조환자경과14천적치료후，대량조환자적림상효과、약물적불량반응이급발작정황진행관찰화비교。결과：경과림상연구결과현시，실험조채용곡미타진연합은심과립진행치료，총유효솔명현고우대조조환자，발작차수명현소우대조조，량조환자재림상효과이급발작정황적비교상，구유현저차이성，존재통계학의의，P<0.05；재약물불량반응적발생솔비교상，량조환자균몰유현저차이성，불구유통계학의의，P>0.05。결론：경림상연구표명，채용곡미타진연합은심과립대불은정형심교통환자진행치료，구유현저적림상효과，불량반응교소，구유교고적림상응용개치이급안전성，치득추엄화보급。
Objective:the observation and analysis of clinical effect of Qumei trimetazidine combined with Wenxin Granule in the treatment of unstable angina pectoris. Methods:the clinical research mainly takes 100 patients with unstable angina pectoris from 2009 March to 2012 March as the research object, using random allocation principle, 100 patients are randomly divided into control group and experimental group, each group of each 50 cases, patients in the control group treatment mainly by Qumei trimetazidine treatment, while the patients in the experimental group by Qumei trimetazidine combined with Wenxin Granule for treatment. Two groups of patients after 14 days of treatment, adverse reactions to drugs, clinical effect of two groups of patients and seizures are observed and compared. Results:the clinical study shows, the experimental group is treated by Qumei trimetazidine combined with Wenxin granule, the total efficiency is higher than that of the control group patients, seizure frequency is significantly less than that in the control group, two groups of patients in the clinical effect and attack situation, has the remarkable difference, there is statistically significant, P<0.05;in adverse drug reaction rate comparison, all patients of two groups have no significant difference, which has not statistically significant, P>0.05. Conclusion:the clinical study shows that, the treatment of patients with unstable angina pectoris are Qumei trimetazidine combined with Wenxin granule, has significant clinical effect, less adverse reaction, it has high value and safety in clinical application, and is worthy of promotion and popularization.