国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2013年
21期
3342-3345
,共4页
铜绿假单胞菌%分布%耐药性%合理用药
銅綠假單胞菌%分佈%耐藥性%閤理用藥
동록가단포균%분포%내약성%합리용약
Pseudomonas aeruginosa%Distribution%Drug resistance%Rational use of drugs
目的 了解铜绿假单胞菌(Pae)在医院感染中的分布特征及耐药性,为临床正确使用抗生素提供实验室依据.方法 回顾性分析我院2012年4月至2013年4月各类标本中分离出的352株铜绿假单胞菌,分别对其分布特点、临床检出率和药敏结果进行统计分析.结果 352株Pae的标本分布以痰液为主(149株),占42.33％；其次为创面分泌物(107株),占30.40％.科室分布以烧伤科为主(107株),占30.40％;其次为ICU(47株),占13.35％.对多粘菌E的耐药率最低,仅为0.62％,其次是丁胺卡那(32.56％)、环丙沙星(37.04％)和美罗培南(38.00％),其余抗菌素耐药率均＞40％.结论 我院Pae主要分布在烧伤病房、ICU等科室,耐药率高且呈多重耐药,临床医生应根据药敏结果合理使用抗菌素,及时做好消毒隔离工作.
目的 瞭解銅綠假單胞菌(Pae)在醫院感染中的分佈特徵及耐藥性,為臨床正確使用抗生素提供實驗室依據.方法 迴顧性分析我院2012年4月至2013年4月各類標本中分離齣的352株銅綠假單胞菌,分彆對其分佈特點、臨床檢齣率和藥敏結果進行統計分析.結果 352株Pae的標本分佈以痰液為主(149株),佔42.33％；其次為創麵分泌物(107株),佔30.40％.科室分佈以燒傷科為主(107株),佔30.40％;其次為ICU(47株),佔13.35％.對多粘菌E的耐藥率最低,僅為0.62％,其次是丁胺卡那(32.56％)、環丙沙星(37.04％)和美囉培南(38.00％),其餘抗菌素耐藥率均＞40％.結論 我院Pae主要分佈在燒傷病房、ICU等科室,耐藥率高且呈多重耐藥,臨床醫生應根據藥敏結果閤理使用抗菌素,及時做好消毒隔離工作.
목적 료해동록가단포균(Pae)재의원감염중적분포특정급내약성,위림상정학사용항생소제공실험실의거.방법 회고성분석아원2012년4월지2013년4월각류표본중분리출적352주동록가단포균,분별대기분포특점、림상검출솔화약민결과진행통계분석.결과 352주Pae적표본분포이담액위주(149주),점42.33％；기차위창면분비물(107주),점30.40％.과실분포이소상과위주(107주),점30.40％;기차위ICU(47주),점13.35％.대다점균E적내약솔최저,부위0.62％,기차시정알잡나(32.56％)、배병사성(37.04％)화미라배남(38.00％),기여항균소내약솔균＞40％.결론 아원Pae주요분포재소상병방、ICU등과실,내약솔고차정다중내약,림상의생응근거약민결과합리사용항균소,급시주호소독격리공작.
Objective To provide some evidences for the rational use of antibiotics investigating the distribution characteristics and drug resistance of pseudomonas aeruginosa in the hospital infection.Methods The detection rate,distribution characteristics,and drug sensitivity test findings of 352 strains of pseudomonas aeruginosa isolated from different kinds of clinical specimens in our hospital from April 2012 to April 2013 were retrospectively and statistically analyzed.Results The detection rate of pseudomonas aeruginosa in sputum samples was the highest(149 strains,42.33％),and that in wound secretions(107 strains,30.40％)came the next.P.aeruginosa mainly distributed in burn unit(30.40％) and ICU department(13.35％).Polymyxin E against pseudomonas aeruginosa were the most sensitive,with a resistance rate of 0.62％.The resistance rates to Amikacin,Meropenem,and Ciprofloxacin were 32.56％,38.00％,and 37.04％,respectively.The resistance rates to other antimicrobial agents were all over 40％.Conclusions In our hospital,P.aeruginosa mainly distribute in the burn unit and ICU department.P.aeruginosa has the characteristics of high resistance rate and multidrug resistance.Therefore,the clinicians should choose the antibiotics reasonably according to the antimicrobial susceptibility test results and do well in disinfection and isolation.
