CAJ | 학술논문

目的对于颞叶新皮层存在局灶性损害的癫痫患者,应用颅内电极记录新皮层病灶部位及海马的发作期电活动,以判断海马是否是独立的致痫灶.方法总结8例患者,入选标准:MRI显示一侧颞叶新皮层存在局灶性的损害,双侧海马形态基本正常,无萎缩及肿胀等变化;术后随访1年以上.分析颅内脑电图临床发作及电发作的起源部位.结果颅内脑电图共记录到临床发作65次,电发作16次,其中起源于颞叶内侧的临床发作24次,电发作7次.仅1例患者所有发作均起源于新皮层,其余7例均有独立起源于海马的临床发作或电发作.结论颅内脑电图记录显示在颞叶新皮层存在局灶性损害的癫痫患者,海马是重要的独立致痫区,MRI不能提供确切的证据,颅内电极记录是确定致痫灶的可靠方法.
목적 대우섭협신피층존재국조성손해적전간환자,응용로내전겁기록신피층병조부위급해마적발작기전활동,이판단해마시부시독립적치간조.방법 총결8례환자,입선표준:MRI현시일측섭협신피층존재국조성적손해,쌍측해마형태기본정상,무위축급종창등변화;술후수방1년이상.분석로내뇌전도림상발작급전발작적기원부위.결과 로내뇌전도공기록도림상발작65차,전발작16차,기중기원우섭협내측적림상발작24차,전발작7차.부1례환자소유발작균기원우신피층,기여7례균유독립기원우해마적림상발작혹전발작.결론 로내뇌전도기록현시재섭협신피층존재국조성손해적전간환자,해마시중요적독립치간구,MRI불능제공학절적증거,로내전겁기록시학정치간조적가고방법.
Objective For patients with lesional lateral temporal lobe epilepsy,whether or not to resection the hippocampal is difficult to decide.We analyzed the intracranial EEG of patients with localized lesion in the lateral temporal cortex.Methods We studied 8 patients who satisfied the following criteria:MRI showed a lesion localized at the lateral temporal lobe.Postoperative follow-up was more than Ⅰ year.Results A total of 65 complex partial seizures and 16 subclinical seizures were recorded,among them,24 clinical seizures and 7 subclinical seizures arising from hippocampal.7 patients had ictal discharges originating from the hippocampal.Conclusions Intracranial EEG analysis revealed that independent ictal discharges from the hippocampal in patients with localized lesion in the lateral cortex,hippocampal maybe an independent epilepticgenic onset zone.