中国实验方剂学杂志
中國實驗方劑學雜誌
중국실험방제학잡지
CHINESE JOURNAL OF EXPERIMENTAL TRADITIONAL MEDICAL FORMULAE
2013年
2期
108-113
,共6页
毛莹%张贵君%刘晶晶%董文茜%张雅楠
毛瑩%張貴君%劉晶晶%董文茜%張雅楠
모형%장귀군%류정정%동문천%장아남
葛根芩连汤%药效组分%HPLC
葛根芩連湯%藥效組分%HPLC
갈근금련탕%약효조분%HPLC
目的:分析测定葛根芩连汤中的14种药效组分,为建立其与临床疗效对应的质量标准提供技术和思路.方法:按照传统经方制备葛根芩连汤,采用高效液相色谱法(HPLC)对其药效组分进行测定.结果:葛根芩连汤中的14种药效组分,即葛根素、大豆苷、大豆苷元、黄芩苷、汉黄芩苷、黄芩素、汉黄芩素、盐酸小檗碱、盐酸巴马汀、盐酸药根碱、盐酸表小檗碱、盐酸黄连碱、甘草酸铵、甘草苷的含量分别为1.6737％,0.1533％,0.0473％,0.4480％,0.0916％,0.0123％,0.0067％,0.0955％,0.0343％,0.0438％,0.0360％,0.0483％,0.1103％,0.1580％.结论:所采用的HPLC法快速、简便,所测得的葛根芩连汤中的药效组分可作为其质量控制的科学指标.
目的:分析測定葛根芩連湯中的14種藥效組分,為建立其與臨床療效對應的質量標準提供技術和思路.方法:按照傳統經方製備葛根芩連湯,採用高效液相色譜法(HPLC)對其藥效組分進行測定.結果:葛根芩連湯中的14種藥效組分,即葛根素、大豆苷、大豆苷元、黃芩苷、漢黃芩苷、黃芩素、漢黃芩素、鹽痠小檗堿、鹽痠巴馬汀、鹽痠藥根堿、鹽痠錶小檗堿、鹽痠黃連堿、甘草痠銨、甘草苷的含量分彆為1.6737％,0.1533％,0.0473％,0.4480％,0.0916％,0.0123％,0.0067％,0.0955％,0.0343％,0.0438％,0.0360％,0.0483％,0.1103％,0.1580％.結論:所採用的HPLC法快速、簡便,所測得的葛根芩連湯中的藥效組分可作為其質量控製的科學指標.
목적:분석측정갈근금련탕중적14충약효조분,위건립기여림상료효대응적질량표준제공기술화사로.방법:안조전통경방제비갈근금련탕,채용고효액상색보법(HPLC)대기약효조분진행측정.결과:갈근금련탕중적14충약효조분,즉갈근소、대두감、대두감원、황금감、한황금감、황금소、한황금소、염산소벽감、염산파마정、염산약근감、염산표소벽감、염산황련감、감초산안、감초감적함량분별위1.6737％,0.1533％,0.0473％,0.4480％,0.0916％,0.0123％,0.0067％,0.0955％,0.0343％,0.0438％,0.0360％,0.0483％,0.1103％,0.1580％.결론:소채용적HPLC법쾌속、간편,소측득적갈근금련탕중적약효조분가작위기질량공제적과학지표.
