中华创伤杂志
中華創傷雜誌
중화창상잡지
Chinese Journal of Traumatology
2013年
7期
657-660
,共4页
马杰%郭明锋%蔡卫林%丁智超%励俊
馬傑%郭明鋒%蔡衛林%丁智超%勵俊
마걸%곽명봉%채위림%정지초%려준
烧伤%葡萄球菌皮肤感染%复合溶葡萄球菌酶消毒剂
燒傷%葡萄毬菌皮膚感染%複閤溶葡萄毬菌酶消毒劑
소상%포도구균피부감염%복합용포도구균매소독제
Burns%Staphylococcal skin infection%Compound lysostaphin disinfectant
目的 比较复合溶葡萄球菌酶(Fudan enzyme,FE)消毒剂(百克瑞)和传统消毒剂碘伏防治烧伤创面革兰阳性(G+)球菌感染的疗效. 方法 收集60例浅Ⅱ度烧伤患者(烧伤面积1％ ～5％,年龄18 ～50岁),每例患者治疗前创面取分泌物做细菌培养,其中20例培养出金黄色葡萄球菌(staphylococcus aureus,SA),按随机数字表法分为对照组和试验组,每组10例.20例培养出表皮葡萄球菌(staphylococcus epidermidis,SE),按随机数字表法分为对照组和试验组,每组10例.20例培养出肠球菌(enterococcus,EC),按随机数字表法分为对照组和试验组,每组10例.试验组用百克瑞浸透4层无菌纱布外敷创面换药,对照组用碘伏浸透4层无菌纱布外敷创面换药,均每日换药1次,治疗5d期间每天每例患者创面取分泌物培养.比较各组患者的愈合情况.结果 经过5d治疗后,SA感染创面,试验组10例全部转阴,对照组3例转阴(P＜0.01).SE感染创面,试验组10例全部转阴,对照组6例转阴(P＜0.05).EC感染创面,试验组9例转阴,对照组7例转阴(P＞0.05).试验组平均愈合时间为(10.87±1.93)d,对照组为(13.31±2.89)d(P＜0.05). 结论 百克瑞能有效防止烧伤创面常见G+球菌感染,并能促进创面愈合.
目的 比較複閤溶葡萄毬菌酶(Fudan enzyme,FE)消毒劑(百剋瑞)和傳統消毒劑碘伏防治燒傷創麵革蘭暘性(G+)毬菌感染的療效. 方法 收集60例淺Ⅱ度燒傷患者(燒傷麵積1％ ～5％,年齡18 ～50歲),每例患者治療前創麵取分泌物做細菌培養,其中20例培養齣金黃色葡萄毬菌(staphylococcus aureus,SA),按隨機數字錶法分為對照組和試驗組,每組10例.20例培養齣錶皮葡萄毬菌(staphylococcus epidermidis,SE),按隨機數字錶法分為對照組和試驗組,每組10例.20例培養齣腸毬菌(enterococcus,EC),按隨機數字錶法分為對照組和試驗組,每組10例.試驗組用百剋瑞浸透4層無菌紗佈外敷創麵換藥,對照組用碘伏浸透4層無菌紗佈外敷創麵換藥,均每日換藥1次,治療5d期間每天每例患者創麵取分泌物培養.比較各組患者的愈閤情況.結果 經過5d治療後,SA感染創麵,試驗組10例全部轉陰,對照組3例轉陰(P＜0.01).SE感染創麵,試驗組10例全部轉陰,對照組6例轉陰(P＜0.05).EC感染創麵,試驗組9例轉陰,對照組7例轉陰(P＞0.05).試驗組平均愈閤時間為(10.87±1.93)d,對照組為(13.31±2.89)d(P＜0.05). 結論 百剋瑞能有效防止燒傷創麵常見G+毬菌感染,併能促進創麵愈閤.
목적 비교복합용포도구균매(Fudan enzyme,FE)소독제(백극서)화전통소독제전복방치소상창면혁란양성(G+)구균감염적료효. 방법 수집60례천Ⅱ도소상환자(소상면적1％ ～5％,년령18 ～50세),매례환자치료전창면취분비물주세균배양,기중20례배양출금황색포도구균(staphylococcus aureus,SA),안수궤수자표법분위대조조화시험조,매조10례.20례배양출표피포도구균(staphylococcus epidermidis,SE),안수궤수자표법분위대조조화시험조,매조10례.20례배양출장구균(enterococcus,EC),안수궤수자표법분위대조조화시험조,매조10례.시험조용백극서침투4층무균사포외부창면환약,대조조용전복침투4층무균사포외부창면환약,균매일환약1차,치료5d기간매천매례환자창면취분비물배양.비교각조환자적유합정황.결과 경과5d치료후,SA감염창면,시험조10례전부전음,대조조3례전음(P＜0.01).SE감염창면,시험조10례전부전음,대조조6례전음(P＜0.05).EC감염창면,시험조9례전음,대조조7례전음(P＞0.05).시험조평균유합시간위(10.87±1.93)d,대조조위(13.31±2.89)d(P＜0.05). 결론 백극서능유효방지소상창면상견G+구균감염,병능촉진창면유합.
Objective To compare the effect of Baikerui compound lysostaphin (FE complex phosphoesterasum) disinfectant and povidone iodine in treatment of burn wound infection resulted from gram-positive (G ±) coccus.Methods The study involved 60 patients with superficial second degree burns (1％-5％ TBSA； age range of 18-50 years).All the patients received bacterial culturing of wound secretions prior to treatment.Every 20 patients were indentified with infection of staphylococcus aureus (SA),staphylococcus epidermidis (SE),and enterococcus (EC) respectively and randomized into control group and experiment group,with 10 patients per group.Patients allocated to the experiment group were covered with four-layer sterile gauze soaked into the Baikerui compound lysostaphin disinfectant,while the patients in the control group were treated with four-layer sterile gauze soaked into the povidone iodine.Dressing was changed once a day.Wound culturing was performed again at each day of the 5-day treatment.Wound healing was compared among each group.Results SA wound infection turned negative for all the 10 patients in experimental group and three patients in control group (P ＜ 0.01).SE wound infection turned negative for all the 10 patients in experimental group and six patients in control group (P ＜ 0.05).EC wound infection turned negative for nine patients in experimental group and seven patients in control group (P ＞ 0.05).Mean wound healing time was (10.87 ± 1.93) days for experimental group and (13.31 ± 2.89) days for control group (P ＜ 0.05).Conclusion Baikerui compound lysostaphin disinfectant can effectively prevent burn wound infection with common G + coccus and accelerate wound healing.
