CAJ | 학술논문

目的：探讨宫颈锥型切除术在高级别宫颈上皮内瘤变(HG CIN, CIN3)治疗中的诊断价值。方法：回顾我院妇科因阴道镜下多点活检病理诊断为CIN3的76例患者,采用前后对照法,对术前阴道镜下多点活检、术后组织学结果进行对比分析。结果：76例CIN3患者中40例入院后拟行全子宫切除术,全子宫切除术前均行诊断性宫颈锥型切除术,36例直接行宫颈锥型切除术治疗,76例患者锥切术后石蜡切片病理与阴道镜下多点活检病理结果对照,一致者49例,占64.47％,不一致者27例,占35.53％,锥切术后有5例组织病理较术前活检组织病理升级,占6.58％,5例术后病理结果为早期浸润癌。其中3例Ia1期,1例Ia2期,1例Ib1期。结论：阴道镜下多点活检具有一定的局限性,拟行全子宫切除术前行宫颈锥型切除术进一步明确诊断是必要的。
목적：탐토궁경추형절제술재고급별궁경상피내류변(HG CIN, CIN3)치료중적진단개치。방법：회고아원부과인음도경하다점활검병리진단위CIN3적76례환자,채용전후대조법,대술전음도경하다점활검、술후조직학결과진행대비분석。결과：76례CIN3환자중40례입원후의행전자궁절제술,전자궁절제술전균행진단성궁경추형절제술,36례직접행궁경추형절제술치료,76례환자추절술후석사절편병리여음도경하다점활검병리결과대조,일치자49례,점64.47％,불일치자27례,점35.53％,추절술후유5례조직병리교술전활검조직병리승급,점6.58％,5례술후병리결과위조기침윤암。기중3례Ia1기,1례Ia2기,1례Ib1기。결론：음도경하다점활검구유일정적국한성,의행전자궁절제술전행궁경추형절제술진일보명학진단시필요적。
Objective: To investigate the diagnostic value of cervical conization in the treatment of high-grade cervical intraepithelial neoplasia(HG CIN, CIN3).Methods:The 76 cases of CIN3 diagnosed by colposcopic multiple biopsies at the Aviation General Hospital,who accepted operation treatment.We analyzed retrospectively focusing on the comparative study in pathology between preoperative colposcopic multiple biopsies and postoperative tissue examination results.Results:The 40 cases of 76 accepted cervical conization for diagnosis before total hysterectomy.36 cases of 76 accepted cervical conization for treatment.Compared with colposcopic multiple biopsy,the histological paraffin section results after operations were identical in 49 cases (64.47%),and not identical in 27 cases (35.53%),5 cases (6.58%) of them upgraded to early invasive cancer.Conclusion:The colposcopic multiple biopsies is limited,Cervical conization based on colposcopic multiple biopsies is important for diagnosis before total hysterectomy.