CAJ | 학술논문

目的：探讨糖尿病(DM)患者血糖与血清镁、磷、钙含量相关性,分析临床意义。方法：选取在我院健康管理中心体检的中老年人员618例,男313例,女305例,年龄40～70岁,平均58.8岁。按有无DM分成2组：A组(DM组)：男153例,女159例,年龄40～70岁,平均58.2岁。B组(糖耐量正常组)：男160例,女146例,年龄40～70岁,平均59.6岁。所以人员均无严重钙、磷、镁代谢紊乱,无慢性腹泻、呕吐等,未使用抗肿瘤药物、氨基糖甙类抗生素等,未长期或大量使用利尿剂。由护士对618例体检者进行采血取样,共获血清样本618份,血清样本经处理,进行了血糖、血清镁、血清磷、血清钙水平的测定。结果：(1)A组比B组血糖水平明显增高(P<0.01)；与B组比较,A组存在钙缺乏(P<0.01)及镁缺乏(P<0.01),两组血清磷水平差异不显著(P>0.05)。(2)血镁含量,血钙含量与血糖水平之间呈显著负相关(r=-0.331、-0.282, P<0.01)；血磷与血糖水平之间无相关性(r=-0.031,P>0.05)。结论：血清钙、血清镁和DM的发生及发展有密切相关,对于大规模体检人群尤其是DM及其高危人群应及时检测其血清钙、血清镁含量,采取相应措施对纠正糖代谢异常及电解质紊乱,保持体内代谢平衡,对预防及治疗DM及其并发症有重要的指导意义。
목적：탐토당뇨병(DM)환자혈당여혈청미、린、개함량상관성,분석림상의의。방법：선취재아원건강관리중심체검적중노년인원618례,남313례,녀305례,년령40～70세,평균58.8세。안유무DM분성2조：A조(DM조)：남153례,녀159례,년령40～70세,평균58.2세。B조(당내량정상조)：남160례,녀146례,년령40～70세,평균59.6세。소이인원균무엄중개、린、미대사문란,무만성복사、구토등,미사용항종류약물、안기당대류항생소등,미장기혹대량사용이뇨제。유호사대618례체검자진행채혈취양,공획혈청양본618빈,혈청양본경처리,진행료혈당、혈청미、혈청린、혈청개수평적측정。결과：(1)A조비B조혈당수평명현증고(P<0.01)；여B조비교,A조존재개결핍(P<0.01)급미결핍(P<0.01),량조혈청린수평차이불현저(P>0.05)。(2)혈미함량,혈개함량여혈당수평지간정현저부상관(r=-0.331、-0.282, P<0.01)；혈린여혈당수평지간무상관성(r=-0.031,P>0.05)。결론：혈청개、혈청미화DM적발생급발전유밀절상관,대우대규모체검인군우기시DM급기고위인군응급시검측기혈청개、혈청미함량,채취상응조시대규정당대사이상급전해질문란,보지체내대사평형,대예방급치료DM급기병발증유중요적지도의의。
Objective:To explore diabetes (DM) blood glucose and serum magnesium, phosphorus, calcium content correlation analysis of clinical significance. Methods:Select Health Management Center in our hospital examination in elderly people 618 cases, 313 cases of male, female 305 cases, aged 40 to 73 years, mean 58.8 years. By DM divided into two groups:A group (DM group):male 153 cases, female 159 cases, aged 42 to 73 years, mean 59.6 years old. Group B (NGT):male 160 cases, female 146 cases, aged 40 to 70 years, mean 58.2 years old. So people had no serious calcium, phosphorus, magnesium metabolism, without chronic diarrhea, vomiting, unused anticancer drugs, aminoglycoside antibiotics, not long-term or heavy use of diuretics. Physical examination by a nurse who carried on 618 cases of blood sampling, winning 618 serum samples were serum samples treated for blood glucose, serum magnesium, serum phosphorus, serum calcium levels measured.Results:(1) A group than in blood glucose levels were significantly higher in group B (P<0.01);Compared with group B, A group presence of calcium deficiency (P<0.01) and magnesium deficiency (P<0.01), serum phosphorus levels of the two groups was not significant (P>0.05). (2) blood magnesium levels, serum calcium levels and blood glucose levels showed a significant negative correlation between (r = -0.331, -0.282, P<0.01); phosphorus and no correlation between blood glucose levels (r = -0.031, P>0.05).Conclusion:Serum calcium, serum magnesium and DM is closely related to the occurrence and development, especially for large medical groups at high risk of DM and its timely detection of serum calcium, serum magnesium levels, take appropriate measures to correct abnormal glucose metabolism and electrolyte imbalance, to maintain metabolic balance in the prevention and treatment of DM and its complications has important guiding significance.