CAJ | 학술논문

[目的]总结开展抗菌药物专项整治活动的干预措施及成效。[方法]统计分析2010年7月1日至2011年6月30日（干预前）及2011年7月1日至2012年6月30日（干预后）干预前后抗菌药物合理应用指标数据。采取健全制度、签定管理责任状及具体措施进行干预，比较干预前后门诊患者抗菌药物处方比例、住院患者抗菌药物使用率、住院患者抗菌药物使用强度、Ⅰ类切口手术患者预防使用抗菌药物比例、抗菌药物费用占药费总额的百分率五项指标的变化。[结果]五项指标干预后均较干预前显著下降（ P ＜0．05）。[结论]抗菌药物临床应用专项整治活动干预措施可行有效，对抗菌药物安全、有效、经济的合理使用起到了积极促进作用。
[목적]총결개전항균약물전항정치활동적간예조시급성효。[방법]통계분석2010년7월1일지2011년6월30일（간예전）급2011년7월1일지2012년6월30일（간예후）간예전후항균약물합리응용지표수거。채취건전제도、첨정관리책임상급구체조시진행간예，비교간예전후문진환자항균약물처방비례、주원환자항균약물사용솔、주원환자항균약물사용강도、Ⅰ류절구수술환자예방사용항균약물비례、항균약물비용점약비총액적백분솔오항지표적변화。[결과]오항지표간예후균교간예전현저하강（ P ＜0．05）。[결론]항균약물림상응용전항정치활동간예조시가행유효，대항균약물안전、유효、경제적합리사용기도료적겁촉진작용。
[Objective]To explore the effect of special rectification intervention of antibacterials in our hos-pital .[Methods] The indexes and data of rational usage of antibacterials from July 1 ,2010 to June 30 ,2011 (before intervention) and July 1 ,2011 to June 30 ,2012(after intervention) were analyzed by statistics .Per-fect system ,responsibility certificate and specific measures were adopted for intervention .The percentage of antibacterials prescriptions for outpatients ,the use ratio of antibacterials for inpatients ,the use strength of an-tibacterials for inpatients ,the percentage of prophylactic antibacterials for patients undergoing type I incision operation and the percentage of antibacterials in total pharmaceutical fees were compared between before and after treatment .[Results] Compared before treatment ,the above five indexes decreased significantly after in-tervention( P <0 .05) .[Conclusion] The intervention measures of special rectification for clinical application of antibacterials are feasible and effective ,and can actively promote safe ,effective and economic and rational use of antibacterials .