CAJ | 학술논문

胸腺素β4（thymosin beta4，Tβ4）作为一种多功能的多肽，广泛分布于哺乳动物和其他脊椎动物中。Tβ4的促进血管再生、神经轴突再生、肿瘤生长和伤口愈合、抑制炎症等功能已经成为国内外研究的焦点，并且Tβ4可能成为治疗卒中的新靶点。本文就Tβ4在血管再生中的研究进展做一综述。
흉선소β4（thymosin beta4，Tβ4）작위일충다공능적다태，엄범분포우포유동물화기타척추동물중。Tβ4적촉진혈관재생、신경축돌재생、종류생장화상구유합、억제염증등공능이경성위국내외연구적초점，병차Tβ4가능성위치료졸중적신파점。본문취Tβ4재혈관재생중적연구진전주일종술。
Thymosin beta 4 (Tβ4) is a pleiotropic peptide which is widely distributed in mammals and other vertebrates, and participates in several cellular events including promotion angiogenesis, new axon growth, cancerogenesis, wound healing and inhibition of inflammation. Due to the effects of Tβ4 in these events, it may become a new target site of stroke treatment. In this review we discuss the current state of knowledge regarding the effects of Tβ4 on angiogenesis.