CAJ | 학술논문

目的：探讨老年高血压病合并心力衰竭患者采用个性化治疗的临床效果。方法将我院2012年4月至2013年5月收治100例老年高血压合并心衰患者随机分为50例观察组和50例对照组，观察组依据每位患者的不同特点实施个性化治疗，药物治疗选择口服硝普钠联合胺碘酮；对照组采用常规治疗，药物治疗选择口服胺碘酮，对比两组患者的治疗效果。结果治疗有效率，观察组92.0%显著高于对照组76.0%，比较具有统计学差异（P＜0.05）；高血压治疗达标率，观察组显著高于对照组，比较具有统计学差异（P＜0.05）；并发症出现率，观察组为10.0%明显低于对照组30.0%，比较具有统计学差异（P＜0.05）。结论依据老年高血压合并心衰患者的不同特点实施个性化治疗，临床效果显著，降低并发症的出现，值得进行推广。
목적：탐토노년고혈압병합병심력쇠갈환자채용개성화치료적림상효과。방법장아원2012년4월지2013년5월수치100례노년고혈압합병심쇠환자수궤분위50례관찰조화50례대조조，관찰조의거매위환자적불동특점실시개성화치료，약물치료선택구복초보납연합알전동；대조조채용상규치료，약물치료선택구복알전동，대비량조환자적치료효과。결과치료유효솔，관찰조92.0%현저고우대조조76.0%，비교구유통계학차이（P＜0.05）；고혈압치료체표솔，관찰조현저고우대조조，비교구유통계학차이（P＜0.05）；병발증출현솔，관찰조위10.0%명현저우대조조30.0%，비교구유통계학차이（P＜0.05）。결론의거노년고혈압합병심쇠환자적불동특점실시개성화치료，림상효과현저，강저병발증적출현，치득진행추엄。
Objective To investigate the clinical effect of individualized treatment for elderly hypertension with heart failure. Methods A total of 100 elderly hypertension patients with heart failure admitted to our hospital from April 2012 to May 2013 were randomly divided into observation group (n=50) and control group (n=50). The observation group received individualized treatment in which sodium nitroprusside and amiodarone were orally given, while the control group received conventional treatment in which amiodarone was orally given. The treatment outcomes of the two groups were compared. Results The observation group had a significantly higher overall response rate than the control group (92.0%vs 76.0%, P<0.05). Compared with the control group, the observation group had a significantly higher percentage of individuals with normal blood pressure after treatment (P<0.05). The observation group had a significantly lower rate of complications than the control group (10.0% vs 30.0%, P<0.05). Conclusion Individualized treatment has good clinical effect and reduces complications in elderly hypertension patients with heart failure and holds promise for clinical application.