中国血液流变学杂志
中國血液流變學雜誌
중국혈액류변학잡지
CHINESE JOURNAL OF HEMORHEOLOGY
2013年
4期
712-713,726
,共3页
顾琴%汤继宏%霍洪亮%张利亚%陈旭勤%张兵兵%李岩
顧琴%湯繼宏%霍洪亮%張利亞%陳旭勤%張兵兵%李巖
고금%탕계굉%곽홍량%장리아%진욱근%장병병%리암
脱髓鞘脑病%诊断%自身免疫
脫髓鞘腦病%診斷%自身免疫
탈수초뇌병%진단%자신면역
demyelinating encephalopathy%diagnosis%autoimmune
目的:探讨儿童急性脱髓鞘脑病的临床特征和诊治过程以提高确诊率。方法回顾性分析近5年收治的50例儿童急性脱髓鞘脑病的临床资料。结果50例患儿中以头痛、呕吐起病20例,以视觉障碍起病12例,以情绪障碍起病15例,全身无力、精神差起病8例,惊厥发作起病6例,行走困难、感觉障碍起病5例。经治疗急性期明显好转45例,无效5例、治疗中断8例。缓解再复发7例,死亡2例。结论儿童急性脱髓鞘脑病临床表现复杂多变,容易误诊漏诊。要及时诊断,尽早治疗、坚持用药。
目的:探討兒童急性脫髓鞘腦病的臨床特徵和診治過程以提高確診率。方法迴顧性分析近5年收治的50例兒童急性脫髓鞘腦病的臨床資料。結果50例患兒中以頭痛、嘔吐起病20例,以視覺障礙起病12例,以情緒障礙起病15例,全身無力、精神差起病8例,驚厥髮作起病6例,行走睏難、感覺障礙起病5例。經治療急性期明顯好轉45例,無效5例、治療中斷8例。緩解再複髮7例,死亡2例。結論兒童急性脫髓鞘腦病臨床錶現複雜多變,容易誤診漏診。要及時診斷,儘早治療、堅持用藥。
목적:탐토인동급성탈수초뇌병적림상특정화진치과정이제고학진솔。방법회고성분석근5년수치적50례인동급성탈수초뇌병적림상자료。결과50례환인중이두통、구토기병20례,이시각장애기병12례,이정서장애기병15례,전신무력、정신차기병8례,량궐발작기병6례,행주곤난、감각장애기병5례。경치료급성기명현호전45례,무효5례、치료중단8례。완해재복발7례,사망2례。결론인동급성탈수초뇌병림상표현복잡다변,용역오진루진。요급시진단,진조치료、견지용약。
Objective To discuss the clinic characteristics and diagnosis, treatment of the children with acute demyelinating encephalopathy, so as to increase diagnosis rate. Methods We reviewed retrospectively the clinic data of acute demyelinating encephalopathy in the 50 children, who were admitted to our hospital in the past ifve years. Results There were 20 cases of headache, vomiting onset. The onset of visual impairment in 12 cases and mood disorders in 15 cases occurred. General weakness, poor mental onset was in 8 cases. 6 cases of seizure on-set occurred. Dififcult walking, sensory disturbance onset were in 5 cases. 45 cases signiifcantly improved by the treatment, 5 cases were ineffective, 8 cases were of treatment interruption. 7 cases were ease recurrence, 2 cases died. Conclusion Clinical manifestations in children with acute demyelinating encephalopathy were complicated and easy to misdiagnose. Timely diagnosis, early treatment and being adhere to medication are of great impor-tance.