CAJ | 학술논문

本文探讨了公驼宝克对氢化可的松注射液所致肾阳虚大鼠的影响。采用氢化可的松注射液肌肉注射14d建立肾阳虚大鼠模型后，以宝克作为受试物进行灌胃干预14d。观察大鼠外观、称量造模前后体重变化和睾丸病理组织学变化。同时检测肾阳虚大鼠血清中睾酮（T）、促甲状腺激素（TSH）、血肌酐（Scr）、尿素氮（BUN）、一氧化氮（NO）、超氧化物歧化酶（SOD）的含量。结果显示宝克对肾阳虚大鼠所表现出的”耗竭”现象逐渐减轻，同时发现宝克具有增加体重，升高T，降低TSH、Scr和BUN含量，提高SOD和NO含量，减轻睾丸病理改变的特性。实验表明宝克能明显改善肾阳虚大鼠的症状。
본문탐토료공타보극대경화가적송주사액소치신양허대서적영향。채용경화가적송주사액기육주사14d건립신양허대서모형후，이보극작위수시물진행관위간예14d。관찰대서외관、칭량조모전후체중변화화고환병리조직학변화。동시검측신양허대서혈청중고동（T）、촉갑상선격소（TSH）、혈기항（Scr）、뇨소담（BUN）、일양화담（NO）、초양화물기화매（SOD）적함량。결과현시보극대신양허대서소표현출적”모갈”현상축점감경，동시발현보극구유증가체중，승고T，강저TSH、Scr화BUN함량，제고SOD화NO함량，감경고환병리개변적특성。실험표명보극능명현개선신양허대서적증상。
In this paper, the influence of male camel Bokhi on the rats of Kidney Yang Deficiency was studied. The rats model groups of Kidney Yang Deficiency were established by intramuscular injecting hydrocortisone for 14 days, and then the rats were treated by oral administration of Bokhi for 14 days. The appearance, the changes of weight gain and histological changes of experimental rats were observed. Meanwhile, the content of testesterone (T) , thyroid stimulating hormone(TSH), serum creatinine(Scr) , blood urea nitrogen (BUN), nitric oxide( NO), superoxide dismutase(SOD) in rats serum were detected. The result showed that the "exhaustion" phenomenon of the rats caused by deficiency of Kidney Yang were gradually alleviated by Bokhi which also improved the weight, testesterone(T), superoxide dismutase(SOD) and nitric oxide (NO). The contents of thyroid stimulating h armone (TSH), serum creatinine (Scr), serum urea nitrogen(BUN) and histological changes were reduced. Through the experiment, it was demonstrated that Bokhi can improve the rats of Kidney Yang Deficiency.