白血病·淋巴瘤
白血病·淋巴瘤
백혈병·림파류
JOURNAL OF LEUKEMIA & LYMPHOMA
2014年
4期
244-247
,共4页
移植物抗宿主病,急性%造血干细胞移植,异基因%诊断%治疗
移植物抗宿主病,急性%造血榦細胞移植,異基因%診斷%治療
이식물항숙주병,급성%조혈간세포이식,이기인%진단%치료
Graft versus host disease,acute%Hematopoietic stem cell transplantation,allogeneic%Diagnosis%Treatment
移植物抗宿主病(GVHD)是异基因造血干细胞移植最常见的并发症,分为急性(aGVHD)和慢性(cGVHD)2种类型,其中aGVHD是供者T细胞识别不匹配的宿主多态性组织相容性抗原(MHC)而发生的免疫应答,具有独特发病机制,病理改变及临床表现复杂,可累及多个器官.文章就目前国内外对aGVHD的诊疗进展进行综述.
移植物抗宿主病(GVHD)是異基因造血榦細胞移植最常見的併髮癥,分為急性(aGVHD)和慢性(cGVHD)2種類型,其中aGVHD是供者T細胞識彆不匹配的宿主多態性組織相容性抗原(MHC)而髮生的免疫應答,具有獨特髮病機製,病理改變及臨床錶現複雜,可纍及多箇器官.文章就目前國內外對aGVHD的診療進展進行綜述.
이식물항숙주병(GVHD)시이기인조혈간세포이식최상견적병발증,분위급성(aGVHD)화만성(cGVHD)2충류형,기중aGVHD시공자T세포식별불필배적숙주다태성조직상용성항원(MHC)이발생적면역응답,구유독특발병궤제,병리개변급림상표현복잡,가루급다개기관.문장취목전국내외대aGVHD적진료진전진행종술.
Graft versus host disease is the most common complication of allogeneic hematopoietic stem cell transplantation.It includes two different types,i.e.acute and chronic types.Acute graft versus host disease (aGVHD) is the immune response of T cells from the donor to unmatched major histocompatibility complex (MHC) from the host.It has unique pathogenesis and pathological changes and complex clinical manifestations with multiple organs involved.This paper reviewed the progress from home and abroad in diagnosis and treatment of acute graft versus host disease.
