CAJ | 학술논문

目的分析肺炎支原体(MP)感染与儿童慢性咳嗽的关系,综合血清学试验结果,探讨以大环内酯序贯疗法为主的治疗效果.方法对2011年5月至2012年5月在我院就诊的270例慢性咳嗽儿童采用被动凝集法检测血清MP-IgM抗体进行比较,将130例MP-IgM阳性者分为观察组及对照组.观察组给予大环内酯序贯疗法,对照组给予阿奇霉素治疗,并观察疗效.结果观察组与对照组治疗有效率分别为97.0％、85.9％,差异有统计学意义(P＜0.05)；观察组与对照组血清MP-IgM总转阴率分别为95.5％、82.8％,差异有统计学意义(P＜0.05).结论 MP感染是引起儿童慢性咳嗽的重要致病因素之一,大环内酯类抗生素序贯治疗为主的疗法具有较好的疗效.
목적 분석폐염지원체(MP)감염여인동만성해수적관계,종합혈청학시험결과,탐토이대배내지서관요법위주적치료효과.방법 대2011년5월지2012년5월재아원취진적270례만성해수인동채용피동응집법검측혈청MP-IgM항체진행비교,장130례MP-IgM양성자분위관찰조급대조조.관찰조급여대배내지서관요법,대조조급여아기매소치료,병관찰료효.결과 관찰조여대조조치료유효솔분별위97.0％、85.9％,차이유통계학의의(P＜0.05)；관찰조여대조조혈청MP-IgM총전음솔분별위95.5％、82.8％,차이유통계학의의(P＜0.05).결론 MP감염시인기인동만성해수적중요치병인소지일,대배내지류항생소서관치료위주적요법구유교호적료효.
Objective To analyze the correlation between mycoplasma pneumoniae (MP) infection and chronic cough in children,according to the test results of serological,discuss the macrolides sequential therapy effect.Methods From May 2011 to May 2012 in our hospital 270 cases of chronic cough in children were detected serum MP-IgM antibody by passive agglutination method,130 cases were MP-IgM positive,divided into observation group and control group.The observation group was given macrolide sequential therapy,control group received azithromycin treatment,and we observed the effects of two groups.Results The treatment efficiency:the observation group and the control group were 97.0％ and 85.9％ respectively (P＜0.05),with statistical significance; total serum MPIGM negative rate:the observation group and the control group were 95.5％ and 82.8％ respectively (P＜0.05),with statistical significance.Conclusion MP infection is one of the important pathogenic factors of chronic cough in children,macrolide antibiotic sequential therapy treatment has a better curative effect.