中国医药
中國醫藥
중국의약
CHINA MEDICINE
2013年
3期
393-395
,共3页
孕妇%婴儿,新生%低血糖症
孕婦%嬰兒,新生%低血糖癥
잉부%영인,신생%저혈당증
Pregnant women%Infant,newborn%Hypoglycemia
目的 探讨妊娠期糖代谢异常孕妇分娩前血糖水平与新生儿低血糖的关系.方法 收集本院2004年1-12月385例无严重内科并发症、围产期各项检查和记录完整的足月单胎孕妇病历资料并进行回顾性分析.根据血糖检测结果分为对照组(血糖正常,265例)、妊娠期糖尿病(GDM)组(51例)、50 g葡萄糖激发试验(GCT)/妊娠期糖耐量(GIGT)异常组(69例).对比3组孕妇产前5～10 min血糖水平及新生儿生后1h血糖水平.结果 ①385例足月新生儿中发生低血糖者20例(5.2％),其中对照组、GCT/GIGT异常组和GDM组发生新生儿低血糖者分别为9例(45.0％)、4例(20.0％)和7例(35.0％),3组间两两比较,差异均无统计学意义(均P＞0.05).②对照组、GCT/GIGT异常组和GDM组新生儿生后1h发生低血糖新生儿的血糖均值分别为(2.03±0.87)、(1.85 ±0.58)、(1.46±0.05) mmol/L,GDM组与对照组的差异有统计学意义(P＜0.05),GCT/GIGT异常组与对照组的差异有统计学意义(P＜0.05),GCT/GIGT异常组与GDM组的差异有统计学意义(P＜0.05).③对照组、GCT/GIGT组和GDM组孕妇分娩前5～10 min血糖水平分别为(5.2±1.2)、(5.3±1.5)和(5.3±1.6) mmol/L,与新生儿生后1h低血糖不相关(r值分别为0.102、0.165和0.244,均P＞0.05).结论 孕妇自身疾病会对新生儿的血糖有一定的影响,应对整个孕期的血糖进行监控,对妊娠期糖代谢异常孕妇分娩新生儿出生后应该进行严密监测.
目的 探討妊娠期糖代謝異常孕婦分娩前血糖水平與新生兒低血糖的關繫.方法 收集本院2004年1-12月385例無嚴重內科併髮癥、圍產期各項檢查和記錄完整的足月單胎孕婦病歷資料併進行迴顧性分析.根據血糖檢測結果分為對照組(血糖正常,265例)、妊娠期糖尿病(GDM)組(51例)、50 g葡萄糖激髮試驗(GCT)/妊娠期糖耐量(GIGT)異常組(69例).對比3組孕婦產前5～10 min血糖水平及新生兒生後1h血糖水平.結果 ①385例足月新生兒中髮生低血糖者20例(5.2％),其中對照組、GCT/GIGT異常組和GDM組髮生新生兒低血糖者分彆為9例(45.0％)、4例(20.0％)和7例(35.0％),3組間兩兩比較,差異均無統計學意義(均P＞0.05).②對照組、GCT/GIGT異常組和GDM組新生兒生後1h髮生低血糖新生兒的血糖均值分彆為(2.03±0.87)、(1.85 ±0.58)、(1.46±0.05) mmol/L,GDM組與對照組的差異有統計學意義(P＜0.05),GCT/GIGT異常組與對照組的差異有統計學意義(P＜0.05),GCT/GIGT異常組與GDM組的差異有統計學意義(P＜0.05).③對照組、GCT/GIGT組和GDM組孕婦分娩前5～10 min血糖水平分彆為(5.2±1.2)、(5.3±1.5)和(5.3±1.6) mmol/L,與新生兒生後1h低血糖不相關(r值分彆為0.102、0.165和0.244,均P＞0.05).結論 孕婦自身疾病會對新生兒的血糖有一定的影響,應對整箇孕期的血糖進行鑑控,對妊娠期糖代謝異常孕婦分娩新生兒齣生後應該進行嚴密鑑測.
목적 탐토임신기당대사이상잉부분면전혈당수평여신생인저혈당적관계.방법 수집본원2004년1-12월385례무엄중내과병발증、위산기각항검사화기록완정적족월단태잉부병력자료병진행회고성분석.근거혈당검측결과분위대조조(혈당정상,265례)、임신기당뇨병(GDM)조(51례)、50 g포도당격발시험(GCT)/임신기당내량(GIGT)이상조(69례).대비3조잉부산전5～10 min혈당수평급신생인생후1h혈당수평.결과 ①385례족월신생인중발생저혈당자20례(5.2％),기중대조조、GCT/GIGT이상조화GDM조발생신생인저혈당자분별위9례(45.0％)、4례(20.0％)화7례(35.0％),3조간량량비교,차이균무통계학의의(균P＞0.05).②대조조、GCT/GIGT이상조화GDM조신생인생후1h발생저혈당신생인적혈당균치분별위(2.03±0.87)、(1.85 ±0.58)、(1.46±0.05) mmol/L,GDM조여대조조적차이유통계학의의(P＜0.05),GCT/GIGT이상조여대조조적차이유통계학의의(P＜0.05),GCT/GIGT이상조여GDM조적차이유통계학의의(P＜0.05).③대조조、GCT/GIGT조화GDM조잉부분면전5～10 min혈당수평분별위(5.2±1.2)、(5.3±1.5)화(5.3±1.6) mmol/L,여신생인생후1h저혈당불상관(r치분별위0.102、0.165화0.244,균P＞0.05).결론 잉부자신질병회대신생인적혈당유일정적영향,응대정개잉기적혈당진행감공,대임신기당대사이상잉부분면신생인출생후응해진행엄밀감측.
Objective To study the relationship between blood glucose levels before childbirth of pregnancy sugar metabolism disorders pregnant women and neonatal hypoglycemia.Methods All 385 pregnant women with a single baby were recruited from 1 st January 2004 to 31 st December 2004,without serious physical complications.A retrospective study was performed upon them based on the process of delivery antenatal examination and medical records.It was randomized into three groups according to blood glucose results (normal blood glucose,265 subjects),gestational diabetes (GDM) group (51 subjects),50 g glucose challenge test (GCT)/gestational impaired glucose tolerance (GIGT) abnormal group (69 subjects).Compared with hypoglycemia level of newborn in 1st hour and three groups of pregnant women prenatal 5-10 min.Results ① In the 385 cases of full-term newborns,there were 20 patients (5.2％) with neonatal hypoglycemia.Among them,the control group,GCT/ GIGT abnormal group and GDM group composition of neonatal hypoglycemia occurred more than 9 patients (45.0％),4 cases (20.0％) and 7 cases (35.0％) respectively.There was no significant difference between GCT/GIGT abnormal group and the control group (P ＞ 0.05).There was no significant difference between the GDM group and the control group (P ＞ 0.05).There was no significant difference between the GCT/GIGT abnormal group and the GDM group (P ＞ 0.05).② The mean low blood glucose of the control group,the GCT/GIGT abnormal group and the GDM group newborns after 1 hour was (2.03 ± 0.87),(1.85 ± 0.58),(1.46 ± 0.05)mmol/L respectively.There was significant difference between the GDM group and the control group (P ＜ 0.05),and the GCT/GIGT abnormal group and the control group,the difference was statistically significant (P ＜ 0.05).There was significant difference between the GCT/GIGT abnormal group and the GDM group (P ＜ 0.05).③ The blood glucose of the control group,the GCT/GIGT group and the GDM group before delivery 5-10 min was (5.2 ±1.2),(5.3 ± 1.5) and (5.3 ± 1.6) mmol/L respectively,and there was no relationship with the meanly low blood glucose of newborn 1 hour after birth (r =0.102,0.165 and 0.244,respectively,P ＞ 0.05).Conclusions The whole pregnancy blood glucose control can reduce the incidence of hypoglycemia newborn.These childbirth of pregnancy sugar metabolism disorders pregnant women should be monitored closely.
