中国医药
中國醫藥
중국의약
CHINA MEDICINE
2013年
3期
396-397
,共2页
剖宫产%舒芬太尼%自控静脉镇痛
剖宮產%舒芬太尼%自控靜脈鎮痛
부궁산%서분태니%자공정맥진통
Cesarean section%Sufentanil%Patient controlled intravenous analgesia
目的 比较舒芬太尼与芬太尼用于剖宫产术后镇痛的效果及安全性.方法 将河南省商丘市第一人民医院2011年1-12月行自控静脉镇痛的90例剖宫产患者完全随机分成观察组和对照组,各45例.对照组给予芬太尼静脉自控镇痛；观察组则给予舒芬太尼静脉自控镇痛.比较2组患者术后4、8、12、24、48 h的疼痛视觉模拟评分(VAS),镇静过度、皮肤瘙痒、恶心呕吐、呼吸抑制、通气延长等不良反应的发生情况.结果 观察组患者各时段的术后疼痛VAS评分均优于对照组(P＜0.05)；观察组的不良反应总发生率[33.3％ (15/45)]低于对照组[66.7％ (30/45)],组间差异有统计学意义(p＜0.05).结论 舒芬太尼应用于剖宫产术后自控静脉镇痛优于芬太尼.
目的 比較舒芬太尼與芬太尼用于剖宮產術後鎮痛的效果及安全性.方法 將河南省商丘市第一人民醫院2011年1-12月行自控靜脈鎮痛的90例剖宮產患者完全隨機分成觀察組和對照組,各45例.對照組給予芬太尼靜脈自控鎮痛；觀察組則給予舒芬太尼靜脈自控鎮痛.比較2組患者術後4、8、12、24、48 h的疼痛視覺模擬評分(VAS),鎮靜過度、皮膚瘙癢、噁心嘔吐、呼吸抑製、通氣延長等不良反應的髮生情況.結果 觀察組患者各時段的術後疼痛VAS評分均優于對照組(P＜0.05)；觀察組的不良反應總髮生率[33.3％ (15/45)]低于對照組[66.7％ (30/45)],組間差異有統計學意義(p＜0.05).結論 舒芬太尼應用于剖宮產術後自控靜脈鎮痛優于芬太尼.
목적 비교서분태니여분태니용우부궁산술후진통적효과급안전성.방법 장하남성상구시제일인민의원2011년1-12월행자공정맥진통적90례부궁산환자완전수궤분성관찰조화대조조,각45례.대조조급여분태니정맥자공진통；관찰조칙급여서분태니정맥자공진통.비교2조환자술후4、8、12、24、48 h적동통시각모의평분(VAS),진정과도、피부소양、악심구토、호흡억제、통기연장등불량반응적발생정황.결과 관찰조환자각시단적술후동통VAS평분균우우대조조(P＜0.05)；관찰조적불량반응총발생솔[33.3％ (15/45)]저우대조조[66.7％ (30/45)],조간차이유통계학의의(p＜0.05).결론 서분태니응용우부궁산술후자공정맥진통우우분태니.
Objective To explore the clinical value of sufentanil and fentanyl agonist for analgesia after cesarean section.Methods Totally 90 patients with patient-controlled intravenous analgesia(PCIA) from January 2011 to December 2011 were randomly divided into the observation group and the eontrol group.The control group (45 cases)was given PCIA with fentanyl,while the observation group (45 cases) was given PCIA with sufentanil.Visual analogue scale(VAS) at 4,8,12,24,48 h after the operation,the occurrence of adverse drug reactions,such as pain,pruritus,nausea and vomiting,respiratory depression,ventilation prolongation were compared between the two groups.Results The observation group in 4 h,8 h,12 h,24 h,48 h had higher VAS seores than the control group (P ＜0.05) ; the total adverse reactions rate was 33.3％ in the observation group and that in the control group was 66.7％ (P ＜ 0.05).Conclusion There is a certain value of sufentanil for PCIA after cesarean section.
