中国医药
中國醫藥
중국의약
CHINA MEDICINE
2014年
6期
820-822
,共3页
埃索美拉唑%枸橼酸莫沙必利%反流性食管炎
埃索美拉唑%枸櫞痠莫沙必利%反流性食管炎
애색미랍서%구연산막사필리%반류성식관염
Esomeprazole%Mosapride citrate%Reflux esophagitis
目的 探讨埃索美拉唑联合枸橼酸莫沙必利治疗反流性食管炎(RE)的临床效果.方法 选择2011年3月至2013年3月广州市南沙区第六人民医院收治的RE患者87例.完全随机分为2组:观察组45例,服用埃索美拉唑20 mg,2次/d,同时服用枸橼酸莫沙必利5 mg,3次/d;对照组42例,服用奥美拉唑20 mg,2次/d.2组疗程均为4周,疗程结束后比较2组临床症状和胃镜下的总体疗效.结果 治疗4周后,观察组临床症状改善的总有效率为93.3％ (42/45),明显高于对照组[78.6％(33/42),P＜0.05],2组患者治疗后内镜改善情况比较观察组总有效率[88.9％(40/45)]明显高于对照组76.2％(32/42),P＜0.05].结论 埃索美拉唑联合枸橼酸莫沙必利治疗RE有可以有效缓解患者的临床症状,促进炎症愈合.
目的 探討埃索美拉唑聯閤枸櫞痠莫沙必利治療反流性食管炎(RE)的臨床效果.方法 選擇2011年3月至2013年3月廣州市南沙區第六人民醫院收治的RE患者87例.完全隨機分為2組:觀察組45例,服用埃索美拉唑20 mg,2次/d,同時服用枸櫞痠莫沙必利5 mg,3次/d;對照組42例,服用奧美拉唑20 mg,2次/d.2組療程均為4週,療程結束後比較2組臨床癥狀和胃鏡下的總體療效.結果 治療4週後,觀察組臨床癥狀改善的總有效率為93.3％ (42/45),明顯高于對照組[78.6％(33/42),P＜0.05],2組患者治療後內鏡改善情況比較觀察組總有效率[88.9％(40/45)]明顯高于對照組76.2％(32/42),P＜0.05].結論 埃索美拉唑聯閤枸櫞痠莫沙必利治療RE有可以有效緩解患者的臨床癥狀,促進炎癥愈閤.
목적 탐토애색미랍서연합구연산막사필리치료반류성식관염(RE)적림상효과.방법 선택2011년3월지2013년3월엄주시남사구제륙인민의원수치적RE환자87례.완전수궤분위2조:관찰조45례,복용애색미랍서20 mg,2차/d,동시복용구연산막사필리5 mg,3차/d;대조조42례,복용오미랍서20 mg,2차/d.2조료정균위4주,료정결속후비교2조림상증상화위경하적총체료효.결과 치료4주후,관찰조림상증상개선적총유효솔위93.3％ (42/45),명현고우대조조[78.6％(33/42),P＜0.05],2조환자치료후내경개선정황비교관찰조총유효솔[88.9％(40/45)]명현고우대조조76.2％(32/42),P＜0.05].결론 애색미랍서연합구연산막사필리치료RE유가이유효완해환자적림상증상,촉진염증유합.
Objective To evaluate the clinical benefit effect of esomeprazole combined with mosapride citrate in the treatment of reflux esophagitis.Methods Eighty-seven cases of reflux esophagitis patients were divided into two groups.Observation group (45 cases)took esomeprazole and mosapride citrate; control group (42 cases) had omeprazole.The two groups were treated for 4 weeks.The total effect of clinical symptoms in two groups and endoscopic findings after the end of treatment were compared.Results After treatment,the total effective rate of clinical symptoms in observation group[93.3％ (42/45)] was significantly higher than that in control group[78.6％ (33/42)] (P ＜ 0.05); the improved signs of endoscopic total efficiency in obversation group [88.9％ (40/45)] was significantly higher than that in the control group(76.2％) (P ＜ 0.05).Conclusion Esomeprazole combined with mosapride citrate has a significant effect on the treatment of reflux esophagitis; they can effectively relieve the clinical symptoms of patients with inflammation and promote healing.
