中国烧伤创疡杂志
中國燒傷創瘍雜誌
중국소상창양잡지
2014年
5期
307-314
,共8页
蒲虹妃%贺全勇%罗成群%朱颉
蒲虹妃%賀全勇%囉成群%硃頡
포홍비%하전용%라성군%주힐
致病菌%流行病学%耐药性%细菌分布%烧伤病房
緻病菌%流行病學%耐藥性%細菌分佈%燒傷病房
치병균%류행병학%내약성%세균분포%소상병방
Pathogenic bacteria%Epidemiology%Drug resistance%Bacteria Distribution%Burn Unit
目的：总结2011-2013年中南大学湘雅三医院烧伤科病房致病菌的分布及耐药情况，为临床提供最新的流行病学资料，以优化临床用药方案。方法收集2011年1月-2013年12月烧伤科送检的1240例患者的2025份标本的细菌培养及药敏检测资料，并与1995-2000年烧伤科送检标本的细菌培养及药敏检测结果进行对比分析。结果近3年烧伤科检出病原菌以革兰阴性菌为主，检出率最高者为铜绿假单胞菌，其次为鲍曼不动杆菌、金黄色葡萄球菌。铜绿假单胞菌对多黏菌素B耐药率最低，为48.4％；鲍曼不动杆菌对替加环素耐药率最低，为48.8％；金黄色葡萄球菌对万古霉素耐药率最低，为5.3％。与1995-2000年的检测结果相比，革兰阴性菌检出率呈上升趋势，革兰阳性菌及真菌检出率呈下降趋势，且优势菌及其抗菌谱变化较大。结论中南大学湘雅三医院烧伤科病房近年来的细菌学分布有所变化，整体上呈现出多重耐药、高耐药性的特征，对临床控制和治疗耐药菌株感染提出了严峻的考验。
目的：總結2011-2013年中南大學湘雅三醫院燒傷科病房緻病菌的分佈及耐藥情況，為臨床提供最新的流行病學資料，以優化臨床用藥方案。方法收集2011年1月-2013年12月燒傷科送檢的1240例患者的2025份標本的細菌培養及藥敏檢測資料，併與1995-2000年燒傷科送檢標本的細菌培養及藥敏檢測結果進行對比分析。結果近3年燒傷科檢齣病原菌以革蘭陰性菌為主，檢齣率最高者為銅綠假單胞菌，其次為鮑曼不動桿菌、金黃色葡萄毬菌。銅綠假單胞菌對多黏菌素B耐藥率最低，為48.4％；鮑曼不動桿菌對替加環素耐藥率最低，為48.8％；金黃色葡萄毬菌對萬古黴素耐藥率最低，為5.3％。與1995-2000年的檢測結果相比，革蘭陰性菌檢齣率呈上升趨勢，革蘭暘性菌及真菌檢齣率呈下降趨勢，且優勢菌及其抗菌譜變化較大。結論中南大學湘雅三醫院燒傷科病房近年來的細菌學分佈有所變化，整體上呈現齣多重耐藥、高耐藥性的特徵，對臨床控製和治療耐藥菌株感染提齣瞭嚴峻的攷驗。
목적：총결2011-2013년중남대학상아삼의원소상과병방치병균적분포급내약정황，위림상제공최신적류행병학자료，이우화림상용약방안。방법수집2011년1월-2013년12월소상과송검적1240례환자적2025빈표본적세균배양급약민검측자료，병여1995-2000년소상과송검표본적세균배양급약민검측결과진행대비분석。결과근3년소상과검출병원균이혁란음성균위주，검출솔최고자위동록가단포균，기차위포만불동간균、금황색포도구균。동록가단포균대다점균소B내약솔최저，위48.4％；포만불동간균대체가배소내약솔최저，위48.8％；금황색포도구균대만고매소내약솔최저，위5.3％。여1995-2000년적검측결과상비，혁란음성균검출솔정상승추세，혁란양성균급진균검출솔정하강추세，차우세균급기항균보변화교대。결론중남대학상아삼의원소상과병방근년래적세균학분포유소변화，정체상정현출다중내약、고내약성적특정，대림상공제화치료내약균주감염제출료엄준적고험。
Obj ective Sum up the distribution of the pathogenic bacteria and the situation of antibiotic resistance during 2011-2013 in wards of the Burns Department of the Third Xiangya Hospital of Central South University to provide the latest epidemiological data , so as to optimize the regimen of clinical treatment .Method The data of bacteria culture and drug resistance profile of 2025 specimens from 1240 patients of burns department during 2011 to 2013 , was collected and analyzed in comparison with the counterpart data of 1995-2000 .Results The dominant detected bacteria in burns de-partment were Gram negative bacteria in recent 3 years.The top one is pseudomonas aeruginosa , followed by acinetobacter-baumannii and staphylococcus aureus .The lowest drug resistant ratio is:Pseudomonas aeruginosato polymyxin B , 48.4 %;Acinetobacterbaumannii to tigecycline , 48.8%;Staphylococcus aureus to vancomycin , 5.3%.Compared with 1995-2000 data, the detectionrate is rising for Gram negative bacteria and lowering for Gram positive bacteria and fungus , and the dom-inant bacteria and its antibacterial spectrum changed a lot .Conclusion The distribution of bacteria in the wards of the Burns Department of the Third Xiangya Hospital of Central South University has changed in recent years , featuring multi-drug resistance and high resistance which is a big challenge for the control and cureof infection of drug resistant strains .
