CAJ | 학술논문

采用8．0 Gy γ射线照射ICR小鼠，探讨富氢水对小鼠辐射损伤的保护作用。结果表明：与单纯照射组相比，照前24小时给水组、照前0．5小时给水组动物的平均存活天数分别提高了2．1天和7．1天，其保护指数分别为1．08和1．26；富氢水组动物的血液学指标检测结果以及脾脏、胸腺脏器重量和脏器系数也优于单纯照射组；而动物体重、血清生化指标、骨髓有核细胞数等指标无明显差异。结果提示，富氢水对于小鼠的辐射损伤具有一定程度的保护作用，其中，照射前0．5小时给水对小鼠的保护作用要优于照前24小时给水和照射后给水。
채용8．0 Gy γ사선조사ICR소서，탐토부경수대소서복사손상적보호작용。결과표명：여단순조사조상비，조전24소시급수조、조전0．5소시급수조동물적평균존활천수분별제고료2．1천화7．1천，기보호지수분별위1．08화1．26；부경수조동물적혈액학지표검측결과이급비장、흉선장기중량화장기계수야우우단순조사조；이동물체중、혈청생화지표、골수유핵세포수등지표무명현차이。결과제시，부경수대우소서적복사손상구유일정정도적보호작용，기중，조사전0．5소시급수대소서적보호작용요우우조전24소시급수화조사후급수。
Through irradiation with 8 .0 Gy gamma rays ,the protective effects were studied of hydrogen-rich water at time given against radiation injury in mice .The results show that ,for the before-irradiation-24 h feed water group and the before-irradiation-0 .5 h feed water group ,average survival time increased 2 .1 and 7 .1 d , respectively ,compared with irradiation-alone group .The protective index was 1 .08 and 1 .26 ,respectively the results of blood and spleen ,thymus organ weight and coefficient of hydrogen-rich water group animal were also better than irradiation-alone group;while the animal body weight ,serum biochemical parameters ,bone marrow nucleated cell count were of no significant difference with irradiation-alone group .Results suggest that hydro-gen-rich water has the protective effects against irradiation injury .The protective effect of the before-irradi-ation-0 .5 h feed water group is better than that of the the before-irradiation-24 h feed water group and the irra-diation-alone group feed water .