CAJ | 학술논문

女性生育力是人类繁衍的珍稀资源，卵巢储备是生育力的决定者和体现者；随着女性年龄增加，卵巢内卵子的数量和质量均呈下降趋势，是影响辅助生殖技术助孕成功率的主要因素。为了指导个体化用药，获得优质卵子，越来越多的临床指标用于预测卵巢储备，成为体外受精前常规检测指标。现对抗苗勒管激素（AMH）和抑制素B（INH B）在预测卵巢功能和ART结局方面的最新研究进展进行综述，认为AMH对卵巢低反应、高反应及卵巢过度刺激综合征（OHSS）均有良好的预测价值；INH B的预测价值并不优于其他指标；目前尚无预测辅助生殖技术妊娠结局的良好指标。
녀성생육력시인류번연적진희자원，란소저비시생육력적결정자화체현자；수착녀성년령증가，란소내란자적수량화질량균정하강추세，시영향보조생식기술조잉성공솔적주요인소。위료지도개체화용약，획득우질란자，월래월다적림상지표용우예측란소저비，성위체외수정전상규검측지표。현대항묘륵관격소（AMH）화억제소B（INH B）재예측란소공능화ART결국방면적최신연구진전진행종술，인위AMH대란소저반응、고반응급란소과도자격종합정（OHSS）균유량호적예측개치；INH B적예측개치병불우우기타지표；목전상무예측보조생식기술임신결국적량호지표。
Female fecundity,which depends on the ovarian reserve,plays important role in human reproduction. The age-related poorer outcome of ART largely attributes to the declined oocyte quality and quantity. Some ovarian reserve tests (ORTs) and predictors have been applied in infertile patients undergoing IVF/ICSI treatment to explore individualized FSH dose regimens. Anti-Müllerian hormone (AMH) and inhibin B (INH B) could be considered as two markers of ovarian reserve and outcomes of ART. It was acceptable that AMH could be used to predict the poor ovarian response,excessive response and ovarian hyperstimulation syndrome,and that INH B was not better predictor than others. In fact,there was a very good predictor to predict accurately the pregnancy outcomes of ART.