CAJ | 학술논문

[目的]探讨糖尿病足截肢的相关危险因素，以降低糖尿病足的截肢率。[方法]回顾性分析2006年3月至2012年3月在本院接受治疗的121例糖尿病足患者的临床资料，比较截肢（截肢组）与未截肢（未截肢组）患者的临床资料及生化指标。[结果]两组患者年龄、病程、吸烟史、高血压史、空腹血糖（FBG）及糖化血红蛋白（HbAlc）水平方面比较差异有显著性（P ＜0．05），但在性别、血脂及糖尿病肾病（DN）的发生率比较无显著差异（P ＞0．05）；糖尿病足截肢率与糖尿病足分级程度、下肢动脉病变程度及周围神经损伤程度呈正相关。[结论]患者病程、年龄、吸烟、血压、血糖、下肢血管病变程度、神经病变程度及糖尿病足程度均为糖尿病足截肢的高危因素，临床可根据患者情况，采取积极措施，减少截肢率，提高患者生活质量。
[목적]탐토당뇨병족절지적상관위험인소，이강저당뇨병족적절지솔。[방법]회고성분석2006년3월지2012년3월재본원접수치료적121례당뇨병족환자적림상자료，비교절지（절지조）여미절지（미절지조）환자적림상자료급생화지표。[결과]량조환자년령、병정、흡연사、고혈압사、공복혈당（FBG）급당화혈홍단백（HbAlc）수평방면비교차이유현저성（P ＜0．05），단재성별、혈지급당뇨병신병（DN）적발생솔비교무현저차이（P ＞0．05）；당뇨병족절지솔여당뇨병족분급정도、하지동맥병변정도급주위신경손상정도정정상관。[결론]환자병정、년령、흡연、혈압、혈당、하지혈관병변정도、신경병변정도급당뇨병족정도균위당뇨병족절지적고위인소，림상가근거환자정황，채취적겁조시，감소절지솔，제고환자생활질량。
[Objective]To explore the related risk factors of diabetic foot amputation in order to reduce the amputation rate of diabetic foot.[Methods]Clinical data of 121 patients with diabetic foot who were treated in our hospital from March 2006 to March 2012 were analyzed retrospectively.Clinical data and biochemical inde-xes were compared between amputation group and non-amputation group.[Results]There were significant differences in the age,the course of disease,smoking history,hypertension history,fasting blood glucose (FBG)and glycosylated hemoglobin(HbAlc)level between two groups(P < 0.05),but there was no signifi-cant difference in sex,blood lipids and the incidence of diabetic nephropathy between two groups(P >0.05). The amputation rate of diabetic foot amputation rate had positive correlation with the grade of diabetic foot, the degree of lower limb artery lesion and peripheral nerve injury.[Conclusion]The patients'course of dis-ease,age,smoking,blood pressure,blood sugar,the degree of lower extremity vascular lesion,neuropathy and diabetic foot were high-risk factors of diabetic foot amputation.According to patients'condition in clinical practice,the active measures should be taken to reduce the amputation rate and improve the quality of life of the patients.