CAJ | 학술논문

目的：总结分析脓毒症患者的血气分析特点以及和预后的相关性。方法收集航天中心医院急诊监护收治的脓毒症患者临床资料和血气分析结果，分析不同病情、不同转归病人的血气特点。结果①入ICU早期，脓毒症、严重脓毒症、脓毒症休克三组间PH和血乳酸水平差异有显著性（P<0.01），病情越重，PH越低，乳酸越高；②存活组患者后期（出ICU时）的PH显著高于早期（入ICU时），乳酸（LAC）水平显著低于早期,P <0.01；病死组患者后期乳酸（LAC）水平显著高于早期；③存活组PH在早期和后期均显著高于病死组,P <0.01；存活组乳酸水平早期和后期均显著低于病死组,P <0.01。结论脓毒症患者PH越低，乳酸越高，预示病情越严重；且存活组和病死组随着病程发展，PH和乳酸向相反方向发展。
목적：총결분석농독증환자적혈기분석특점이급화예후적상관성。방법수집항천중심의원급진감호수치적농독증환자림상자료화혈기분석결과，분석불동병정、불동전귀병인적혈기특점。결과①입ICU조기，농독증、엄중농독증、농독증휴극삼조간PH화혈유산수평차이유현저성（P<0.01），병정월중，PH월저，유산월고；②존활조환자후기（출ICU시）적PH현저고우조기（입ICU시），유산（LAC）수평현저저우조기,P <0.01；병사조환자후기유산（LAC）수평현저고우조기；③존활조PH재조기화후기균현저고우병사조,P <0.01；존활조유산수평조기화후기균현저저우병사조,P <0.01。결론농독증환자PH월저，유산월고，예시병정월엄중；차존활조화병사조수착병정발전，PH화유산향상반방향발전。
Objective To analyzes blood gas analysis of sepsis patients and find its characteristics and its correlation with prognosis. Methods Sepsis patients’data was collected in the emergency intensive care unit (ICU) and analyzed based on different conditions and the characteristics of blood gas. Results ① In ICU early stage, the differences of pH and blood lactate among sepsis group, severe sepsis group and septic shock group were significant P < 0.01. The more severe the patient was, the lower the pH was, and the higher the lactate level was; ② Survivors’pH in ICU late stage was significantly lower than that of early stage, and lactate(LAC) levels were significantly lower than that of early stage P < 0.01; non-survivors’lactate (LAC) in later stage was significantly higher than that in early stage; ③ Survivors’pH were significantly higher than non-survivors in the early and late stage P < 0.01; Survivors’lactic acid levels were significantly lower than non-survivors in the early and late stage P < 0.01. Conclusion The lower the sepsis patients’pH is, the higher the lactic acid is, indicating a more severe condition. pH and lactate in the survivors and non-survivors change to opposite direction.