中国医药导刊
中國醫藥導刊
중국의약도간
CHINESE JOURNAL OF MEDICAL GUIDE
2013年
11期
1777-1778,1780
,共3页
心力衰竭%肾综合征%肾小球滤过率
心力衰竭%腎綜閤徵%腎小毬濾過率
심력쇠갈%신종합정%신소구려과솔
Heart failure%Heart renal syndrome%Glomerular filtration rate
目的：研究慢性心力衰竭(CHF)患者肾功能指标的变化以及心肾功能的相关性。方法：80例CHF患者按NYHA心功能分级分为三组,同期住院非CHF患者30例作对照,行心脏超声及肝肾功能检查,据MDRD公式计算GFR值,对比分析各组间相关参数的水平及其相关性。结果：①随着心功能状况的恶化BUN、Cr、UA进行性上升,GFR进行性下降,组间比较有统计学差异(P<0.05),相关性分析显示LVEF与GFR呈正相关,r值为0.365,P<0.05。②GFR判断肾功能不全患病率为52.5%明显高于以Cr升高判断肾功能不全患病率的17.5%,二者比较有统计学差异(P<0.05)。结论：CHF患者肾功能指标与NYHA心功能分级、LVEF值密切相关,GFR能更好地监测CHF患者的肾功能损伤,临床工作中应加强关注CHF患者的肾功能指标有利于制定合适的治疗方案,提高患者的生存率及生活质量。
目的：研究慢性心力衰竭(CHF)患者腎功能指標的變化以及心腎功能的相關性。方法：80例CHF患者按NYHA心功能分級分為三組,同期住院非CHF患者30例作對照,行心髒超聲及肝腎功能檢查,據MDRD公式計算GFR值,對比分析各組間相關參數的水平及其相關性。結果：①隨著心功能狀況的噁化BUN、Cr、UA進行性上升,GFR進行性下降,組間比較有統計學差異(P<0.05),相關性分析顯示LVEF與GFR呈正相關,r值為0.365,P<0.05。②GFR判斷腎功能不全患病率為52.5%明顯高于以Cr升高判斷腎功能不全患病率的17.5%,二者比較有統計學差異(P<0.05)。結論：CHF患者腎功能指標與NYHA心功能分級、LVEF值密切相關,GFR能更好地鑑測CHF患者的腎功能損傷,臨床工作中應加彊關註CHF患者的腎功能指標有利于製定閤適的治療方案,提高患者的生存率及生活質量。
목적：연구만성심력쇠갈(CHF)환자신공능지표적변화이급심신공능적상관성。방법：80례CHF환자안NYHA심공능분급분위삼조,동기주원비CHF환자30례작대조,행심장초성급간신공능검사,거MDRD공식계산GFR치,대비분석각조간상관삼수적수평급기상관성。결과：①수착심공능상황적악화BUN、Cr、UA진행성상승,GFR진행성하강,조간비교유통계학차이(P<0.05),상관성분석현시LVEF여GFR정정상관,r치위0.365,P<0.05。②GFR판단신공능불전환병솔위52.5%명현고우이Cr승고판단신공능불전환병솔적17.5%,이자비교유통계학차이(P<0.05)。결론：CHF환자신공능지표여NYHA심공능분급、LVEF치밀절상관,GFR능경호지감측CHF환자적신공능손상,림상공작중응가강관주CHF환자적신공능지표유리우제정합괄적치료방안,제고환자적생존솔급생활질량。
Objective:Study of chronic heart failure (CHF) in patients with renal function indexes of change and the correlation of heart kidney function.Methods:80 cases of patients with CHF according to NYHA class into three groups, In 30 cases of CHF patients and cardiac ultrasound and kidney function,calculated according to MDRD GFR values,comparative analysis between the groups and the level of the relevant parameters their relevance.Results:(1)With the deterioration of cardiac function in sexual rise, BUN, Cr and UA GFR progressive decline, comparison between groups was statistically difference (P<0.05). Correlation analysis showed that LVEF and GFR were positively correlated, r value was 0.365, P<0.05. (2) GFR judgment to renal dysfunction prevalence was significantly higher than the 52.5%Cr increases renal dysfunction prevalence rate of 17.5%,Both are statistically significant (P<0.05).Conclusions:CHF patients with renal function indexes closely related with NYHA heart function classification and LVEF value. GFR can better monitoring of CHF patients with renal function injury.Clinical work, attention should be strengthened renal function in patients with CHF is conducive to develop an appropriate treatment plan, improve the survival rate and quality of life.
